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Q＆A

What is your hot research topic?

Recent studies show that ubiquitin modification can occur on non-protein targets. We are developing our research on the elucidation of the roles and regulatory mechanisms of ubiquitin modification on non-proteins.

Have you had any breakthroughs or significant research progress in the last 5 years?

We discovered a novel ubiquitin code that has a unique conjugation pattern using biochemical approaches (Rodriguez et al., 2021). We also revealed that an enzyme responsible for this process regulates inflammation via complex mechanisms by analyzing genetically modified mice (Gomez Diaz et al., 2021).

What kind of background do your lab members have？

Thus far, members from nine countries contributed to our research in the Ikeda Lab, including students sent from other labs, and others with various backgrounds and expertise. All have been highly motivated and full of curiosity.

Do you collaborate with other institutions and universities?

We are collaborating with researchers in Japan and Europe through the connections I made during my 15-year posting in Germany and Austria.

What kind of careers do your Lab's alumni go on to?

Many researchers from my lab have gone on to diverse career paths. Some are continuing science in academia as postdocs, PhD students, or senior research assistants; others are working in pharmaceutical companies.

How do you develop your research?

I hope we will elucidate mechanisms of more flexible types of ubiquitin editing, which may regulate human diseases.