Neuroscience Laboratories

Dynamic Brain Network Laboratory

Prof. KITAZAWA Shigeru Prof. KITAZAWA Shigeru


Cognitive brain science, Spatial cognition, Perception of time, Social cognition, Motor learning

Understanding brain functions as those of dynamic networks

Functions of the human brain ranges from perception, motor control, and cognition, to communication. Since the discovery of Broca’s area in 1861, brain researches has been developed by localizing each individual function to a specific region in the brain. However, any function cannot be achieved in one localized area, each individual column, or single neuron. Functions can only be achieved through dynamic collaboration across multiple “localized” areas of the brain. Our Dynamic Brain Network Laboratory aims at finding the principle of such collaboration across multiple regions. Functions being studied are 1) the perception of time, 2) motor learning, 3) visual stability, and 4) social communication.

Left: Blink-related momentary activation of the default mode network (top) and deactivation of the dorsal attention network (bottom). Right: The precuneus, which occupies the center of the brain network, is likely to be representing the origin of our space and time perception (the here and now).
Please visit Lab home page for more details.


Shigeru Kitazawa Professor kitazawa[at]
Masato Inoue Specially GuestAssociate Professor m-inoue[at]
Kei Watanabe   AssociateProfessor kei_watanabe[at]
Masanori Saruwatari Assistant Professor ms[at]
Mikio Inagaki   
Murai Yuki  
Shibusawa Shuka  
Reiji Tanaka D4  
Kyoko O'neill D2  
Du Qinbo D2  
Suzuki Hirotaka  D2  
Cao Xin Yu D1  
WU HongSheng D1  
Cui Shengbin D2  
Takuto Yamamoto D1  
Chinatsu Marumo Medical student  
 Haruka Kato Technician  
Yoshika kaneda  Secretary  

You could probably reach more information of individual researchers by Research Map and researcher's search of Osaka-U.

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What is your hot research topic?
We are now interested in elucidating the functions of the precuneus. The precuneus, the core region of the default mode network, is likely to represent the origin of our space and time perception (the here and now). The default mode network, which was found to be activated after each eyeblink, occupies the center of the brain network.
What is your breakthrough or research progress in the last 5 years?
1. We found that “the now” is represented in the precuneus (Tang et al., 2021).
2. We found that the dopamine reward sys
3. We found that neurons in the motor and parietal association cortices detect errors in reaching, and provide instructions on how to improve the movement (Inoue et al., 2016, 2018).
What kind of background do your lab members have?
Members in our lab have a variety of backgrounds that range from neurophysiology to cognitive neuroscience and engineering.
Do you collaborate with other institutions and universities?
We are collaborating with researchers at Johns Hopkins University, Lyon University, and others.
What kind of careers do your Lab's alumni go on to?
Some assume positions in universities, research institutes, hospitals, and others in companies.
How do you develop your research?
It is generally accepted that amyloid beta deposits begin to accumulate in the precuneus and the default mode network before the onset of Alzheimer's dementia. Our research on cognitive functions and the brain network will provide significant clues to understand pathophysiology of dementia.

Research Highlights

Publications (Research Articles, Reviews, Books)


J. P. Stroud, K. Watanabe, T. Suzuki, M. G. Stokes and M. Lengyel

Optimal information loading into working memory explains dynamic coding in the prefrontal cortex

PNAS 120(48):e2307991120  2023 PMID:37983510 DOI:10.1073/pnas.2307991120

Watanabe, K., Kadohisa, M., Kusunoki, M., Buckley, M. J. & Duncan, J.

Cycles of goal silencing and reactivation underlie complex problem-solving in primate frontal and parietal cortex

Nature Communications 14(1):5054  2023 PMID:37598206 DOI:10.1038/s41467-023-40676-1

Hanyu, N., Watanabe, K. & Kitazawa, S

Ready to detect a reversal oftime’s arrow: a psychophysicalstudy using short video clipsin daily scenes.

Royal Society Open Science 10(4):230036  2023 PMID:37090963 DOI:10.1098/rsos.230036


Asakage, S. & Nakano, T

The salience network is activated during self-recognition from both first-person and third-person perspectives.

Human Brain mappinng 44(2):559-570  2022 PMID:36129447 DOI:10.1002/hbm.26084

Moharramipour A, Takahashi T, Kitazawa S.

Distinctive modes of cortical communications in tactile temporal order judgment.

Cerebral Cortex, 33(6):2982-2996  2022 PMID:35811300 DOI:10.1093/cercor/bhac255

Tamami Nakano,Takuto Yamamoto

You trust a face like yours.

?Humanities and Social Sciences Communications 9(1):226  2022 DOI:10.1057/s41599-022-01248-8


Chisa Ota, Tamami Nakano

Self-Face Activates the Dopamine Reward Pathway without Awareness

Cerebral Cortex 31(10):4420-4426  2021 PMID:33860315 DOI:10.1093/cercor/bhab096

Tang L, Takahashi T, Shimada T, Komachi M, Imanishi N, Nishiyama Y, Iida T, Otsu Y, Kitazawa S.

Neural correlates of temporal presentness in the precuneus: a cross-linguistic fMRI study based on speech stimuli.

Cerebral Cortex 31(3):1538-1552  2021 PMID:33152751 DOI:10.1093/cercor/bhaa307


Prablanc C, Panico F, Fleury L, Pisella L, Nijboer T, Kitazawa S, Rossetti Y

Adapting terminology: clarifying prism adaptation vocabulary, concepts, and methods.

Neurosci. Res. 153:8-21  2020 PMID:30910735 DOI:10.1016/j.neures.2019.03.003

Nakano T, Uesugi Y

Risk Factors Leading to Preference for Extreme Facial Retouching.

Cyberpsychology Behav. Soc. Netw. 23(1):52-59  2020 PMID:31851844 DOI:10.1089/cyber.2019.0545


Parham Mostame , Ali Moharramipour, Gholam_Ali Hossein_Zadeh, Abbas Babajani_Ferem

Statistical Significance Assessment of Phase Synchrony in the Presence of Background Couplings: An ECoG Study

Brain Topogr. 32(5):882-896  2019 PMID:31129754 DOI:10.1007/s10548-019-00718-8

Mikiko Kadohisa, Kei Watanabe, Makoto Kusunoki, Mark J Buckley, John Duncan

Focused Representation of Successive Task Episodes in Frontal and Parietal Cortex

Cereb. Cortex 30(3):1779-1796  2019 PMID:31690931 DOI:10.1093/cercor/bhz202

Nishirmua N, Uchimura M, Kitazawa S

Automatic encoding of a target position relative to a natural scene

J. Neurophysiol. 122(5):1849-1860  2019 PMID:31509471 DOI:10.1152/jn.00032.2018

Rossetti Y, Kitazawa S, Nijboer T

Prism adaptation: From rehabilitation to neural bases

Cortex 111:A1-A6  2019 PMID:30704673 DOI:10.1016/j.cortex.2019.01.002


Nakano T, Miyazaki Y

Blink synchronization is an indicator of interest while viewing videos

Int. J. Psychophysiol. 135:1-11  2018 PMID:30428333 DOI:10.1016/j.ijpsycho.2018.10.012

Inoue M, Kitazawa S

Motor error in parietal area 5 and target error in area 7 drive distinctive adaptation in reaching

Curr. Biol. 28:2250-2262  2018 PMID:29983313 DOI:10.1016/j.cub.2018.05.056

Petitet P, O'Reilly JX, Goncalves AM, Salvan P, Kitazawa S, Hohansen-Berg H, O'Shea J

Causal explanation of individual differences in human sensorimotor memory formation

bioRxiv   2018 DOI:10.1101/255091


Jo T, Yoshimi K, Takahashi T, Oyama G, Hattori N

Dual use of rectangular and triangular waveforms in voltammetry using a carbon fiber microelectrode to differentiate norepinephrine from dopamine

J. Electroanal. Chem. 802:1-7  2017 DOI:10.1016/j.jelechem.2017.08.037

Nakano T, Kuriki C

Transient heart rate acceleration in association with spontaneous eyeblinks

Int. J. Psychophysiol. 121:56-62  2017 PMID:28890182 DOI:10.1016/j.ijpsycho.2017.09.003

Takahashi T, Kitazawa S

Modulation of illusory reversal in tactile temporal order by the phase of posterior alpha rhythm

J. Neurosci. 37(21):5298-5308  2017 PMID:28450538 DOI:10.1523/JNEUROSCI.2899-15.2017

Atsushi Yokoi, Wenjun Bai, Jorn Diedrichsen

Restricted transfer of learning between unimanual and bimanual finger sequences

J. Neurophysiol. 117(3):1043-1051  2017 PMID:27974447 DOI:10.1152/jn.00387.2016

Sekigawa-Hosozawa M, Tanaka K, Shimizu T, Nakano T, Kitazawa S

A group of very preterm children characterized by atypical gaze patterns

Brain Dev. 39(3):187-195  2017 PMID:27814930 DOI:10.1016/j.braindev.2016.10.001

Nakano T, Kitazawa S

Development of long-term event memory in preverbal infants: an eye-tracking study

Sci Rep 7:187-276  2017 PMID:28272489 DOI:10.1038/srep44086

Nakano T

The Right Angular Gyrus Controls Spontaneous Eyeblink Rate: A Combined Structural MRI and TMS Study

Cortex 88:186-191  2017 PMID:28142027 DOI:10.1016/j.cortex.2016.12.022

Chakrabarty M, Nakano T, Kitazawa S

Short-latency allocentric control of saccadic eye movements.

J. Neurophysiol. 117(1):376-387  2017 PMID:27784804 DOI:10.1152/jn.00451.2016


A group of very preterm children characterized by atypical gaze patterns.

Brain Dev. 39(3):218-224  2017 PMID:27814930 DOI:10.1016/j.braindev.2016.10.001


Inoue, M, Uchimura, M, Kitazawa, S

Error signals in motor cortices drive adaptation in reaching.

Neuron 90:1-13  2016 PMID:27181058 DOI:10.1016/j.neuron.2016.04.029

Kuriki S, Tamura R, Igarashi M, Kato M, Nakano T

Similar impressions of humanness for human and artificial singing voices in autism spectrum disorders

Cognition 153:1-5  2016 PMID:27107740 DOI:10.1016/j.cognition.2016.04.004

Wiseman R, Nakano T

Blink and you'll miss it: the role of blinking in the perception of magic tricks

PeerJ 4:e1873  2016 PMID:27069808 DOI:10.7717/peerj.1873

Takahashi T, Takikawa Y, Kawagoe R

Differences in the Pulsatile Component of the Skin Hemodynamic Response to Verbal Fluency Tasks in the Forehead and the Fingertip

Sci Rep 6:20978  2016 PMID:26905432 DOI:10.1038/srep20978

Our ideal candidate (as a graduate student)

We are looking for a highly motivated person to work on our research topics as our lab member.


Dynamic Brain Network Laboratory, Graduate School of Frontier Biosciences, Osaka University,
1-3 Yamadaoka, Suita, Osaka 565-0871 Japan.

TEL: +81-6-6879-4431

E-mail: kitazawa[at] (Prof. Shigeru Kitazawa)

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