FBS Colloquia No.305Laboratory of Medical Biochemistry
Seminar or Lecture |
From the screening system of protein degradation to the development of novel anti-cancer agents Hisakazu Kato [Assistant Professor, Department of Medical Biochemistry] |
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Date and Time | 1 Sep. 2022 (Thu), 12:15~13:00 |
Place | Online (Zoom) | An email will be sent with the meeting URL, ID, and password to all FBS members. |
Language | Japanese |
Contact |
TSUKAMOTO Osamu (Associate Professor) |
From the screening system of protein degradation to the development of novel anti-cancer agents
We are working to elucidate the regulatory mechanisms of energy metabolism in the heart and to develop new therapeutic agents. In the process, we have developed a high-throughput screening system for protein degradation and devised the development of new ATP production-enhancing agents. Given that this screening system can be applied to a wide range of fields, we have recently initiated collaborative research with the Department of Gastrointestinal Surgery, Graduate School of Medicine, to develop new anti-cancer agents for colorectal cancer. In this colloquium, we will introduce the recently revealed mechanism of colorectal cancer onset and progression, together with the screening of novel proteolysis inhibitors.