Unveiling the secret of
germline cells

Research Theme

Although individual animals do die, the species are maintained by sexual reproduction which give rises to next generation. Individuals are just like vehicles in which passenger –genetic information– can ride to be inherited to next generation through germline lineage. As such, germline cells are the most important cells to maintain the species. Drosophila melanogaster is one of the ideal model organisms where we can study gametogenesis. How are germline stem cells maintained in the microenvironment, niche? What is the molecular mechanism that controls germline cells to mature into egg and sperm? How germline genomes are safely guarded by non-coding RNA from transposons attacks? Our group has been addressing such molecular mechanisms for better understanding of gametogenesis.


A graduate student joined!! Welcome aboard, Murakami-kun!
We had a farewell/welcome party! Good bye to Muti-san and Hirayama-san, and welcome aboard, Muarkami-kun!
Fengmei’s PhD thesis was published as preprint in bioRxiv!
Xu F, Suyama R, Inada T, Kawaguchi S, Kai T. (2023) HemK2 functions for sufficient protein synthesis and RNA stability through eRF1 methylation during Drosophila oogenesis.
A research paper collaborated with Dr. Joanne Yew at Hawaii University Manoa was published in Communication Biology!
Suyama R, Cetraro N, Yew J Y, Kai T. (2023) Microbes control Drosophila germline stem cell increase and egg maturation through hormonal pathways. Commun. Biol. 6
At The MBSJ annual meeting 2023 (Meeting Attendance), Professor Kai chaired the Career Path Seminar!
Prof. Kai gave a lecture at the DOJIN FORUM!

A Research Student joined!! Welcome aboard, Zheng-san!
We hosted a farewell lunch party for Fengmei! She always worked hard and had a cheerful spirit. We’ll miss you, but do your best in China!
Fengmei had her doctoral thesis defense! She presented her four years of research work including research student and PhD era, and she was successfully awarded PhD. Congratulations!

Meeting Attendance

The 46th Annual Meeting of the Molecular Biology Society of Japan (Koke)
The meeting of Transformative Research Areas A at Tsuruoka (Tsuruoka, Yamagata)
The 28th Annual Meeting of the RNA Society (Singapore)
The 45th Annual Meeting of the Molecular Biology Society of Japan (Chiba)
2022 EMBO Workshop on PIWI Proteins and piRNAs (Online Conference)
The 44th Annual Meeting of the Molecular Biology Society of Japan (Yokohama, Kanagawa)
The 62nd Annual Drosophila Research Conference (Online Conference)
The 43rd Annual Meeting of the Molecular Biology Society of Japan (Online Conference)
Asia Pacific Drosophila Research Conference 5 (APDRC5) (IISER Pune, India)
The 42nd Annual Meeting of the Molecular Biology Society of Japan (Fukuoka)
RNA Frontier Meeting 2019 (Izu, Shizuoka)
52nd Annual Meeting of the Japanese Society of Developmental Biologists (Osaka)