Welcome to the Fukagawa Lab
We are studying on chromosome segregation.
We especially focus on the centromere and kinetochore.

News

2025.3.10
Dispath has been published in Curr Biol
2024.11.1
Paper has been published in iScience
2024.5.13
A collaborative study has been published in Cell
2023.6.8
Paper has been published in Mol. Cell
2023.2.14
A collaborative study has been published in PNAS: Evolutionary analysis of a complete chicken genome
2023.2.6
Paper has been published in EMBO J.: The cryo-EM structure of the CENP-A nucleosome in complex with ggKNL2
2022.2.14
Paper has been published in Nature Commun.: Recruitment of two Ndc80 complexes via the CENP-T pathway is sufficient for kinetochore functions
2021.1.19
Paper has been published in EMBO J.: Cryo‐EM structure of the CENP‐A nucleosome in complex with phosphorylated CENP‐C
2021.1.8
Paper has been published in Nature Commun.: Bridgin connects the outer kinetochore to centromeric chromatin
2020.11.17
Paper has been published in Cell Rep.: Essentiality of CENP-A depends on its binding mode to HJURP
2020.9.18
Prof. Fukagawa won the Kihara prize from GENETICS SOCIETY OF JAPAN
2019.12.2
Paper has been published in J. Cell Biol.: CDK1-mediated CENP-C phosphorylation modulates CENP-A binding and mitotic kinetochore localization
2018.11.12
We have just started Twitter @tatsuofukagawa1
2018.11.12
Paper has been published in Nature Cell Biol.: Multiple phosphorylations control recruitment of the KMN network onto kinetochores
2018.11.5
Paper has been published in J. Cell Biol.: 3D genomic architecture reveals that neocentromeres associate with heterochromatin regions
2017.7.24
Paper has been published in Dev. Cell: Association of M18BP1/KNL2 with CENP-A nucleosome is essential for centromere formation in non-mammalian vertebrates
2017.1.2
Paper has been published in J. Cell Biol.: Constitutive centromere-associated network controls centromere drift in vertebrate cells
2016.11.4
Paper has been published in Nature Commnications: Acetylation of histone H4 Lysine 5 and 12 is required for CENP-A deposition into centromeres
2015.9.9
Paper has been published in Mol. Biol. Cell: Dynamic changes in the CCAN organization through CENP-C during cell-cycle progression
2015.4.1
Our Lab has been moved to Osaka Univ from NIG
2014.6.23
Paper has been published in Dev. Cell: Centoromere modification for kinetochore assembly
2013.3.25
Paper has been published in Dev. Cell: Neocentromere formation using chromosome engineering.
2013.1.18
Paper has been published in EMBO. J.: Structural core for kinetochore formation.
2012.12.31
Featured in J. Cell Biol. “Comment”.
2012.12.31
Paper has been published in J. Cell Biol.: Creation of cell lines with the“stable” engineered kinetochores.
2012.6.21
Tatsuya Nishino was awarded a Young Scientist Award from Protein Science Society of Japan.
2012.2.3
Paper has been published in Cell: Histone-like structure in the kinetochore.
2012.2.3
Featured in Cell “Previews”
2011.4.29
Paper has been published in Cell: Creation of artificial kinetochores.
2011.4.6
Featured in J. Cell Biol. “In focus”
2011.4.4
Paper has been published in J. Cell Biol.: Kinetochore stretching by tension from spindle microtubules.
2011.2.18
Prof. Fukagawa was appointed Associate Editor on the Editorial Board of Chromosome Research.
2010.9.7
Paper has been published in Genome Res.: Sequencing of centromeric DNA in Chicken.
2009.7.27
Paper has been published in J. Cell Biol.: Identification and characterization of a novel kinetochore protein.
2008.12.12
Paper has been published Cell: Identification of the CENP-T-W complex.
2006.4.16
Paper has been published in Nature Cell Biol.: Identification of centromere proteins required for chromosome segregation.
2004.7.11
Paper has been published in Nature Cell Biol.: Chromosome segregation and RNAi in vertebrate cells.
2002.4.1
Paper has been published in Dev. Cell: Proteins required for innercentromere assembly in vertebrate cells.
2001.8.15
Paper has been published in EMBO J.: Centromere assembly in vertebrate cells.