Unveiling the secret of
germline cells

Research Theme

Although individual animals do die, the species are maintained by sexual reproduction which give rises to next generation. Individuals are just like vehicles in which passenger –genetic information– can ride to be inherited to next generation through germline lineage. As such, germline cells are the most important cells to maintain the species. Drosophila melanogaster is one of the ideal model organisms where we can study gametogenesis. How are germline stem cells maintained in the microenvironment, niche? What is the molecular mechanism that controls germline cells to mature into egg and sperm? How germline genomes are safely guarded by non-coding RNA from transposons attacks? Our group has been addressing such molecular mechanisms for better understanding of gametogenesis.


Miwako Okamura has joined as a technical assistant.
We had welcome party for newcomers in Kai Lab!
Ritsuko Suyama has joined as an assistant professor.
A research paper by Prof. Kai is published in Nature Communications. Teo RYW, Anand A, Sridhar V, Okamura K, Kai T. (2018) Heterochromatin protein 1a functions for piRNA biogenesis predominantly from pericentric and telomeric regions in Drosophila. Nature Commun. 130:1735
New PhD students, Lin-san, Ueda-san, Takami-san and Xenia-san have joined. Welcome aboard!
A review article by Prof. Kai was published in GENETICS as a part of FLY BOOK. Gleason RJ, Anand A, Kai T*, Chen X*. (2018) Protecting and diversifying the germline. GENETICS 208(2):435–471 *Co-corresponding
Prof Kai gave a special lecture to Ibaragi high school students!
Prof. Kai gave a career path talk in English at FBS.
New PhD students, Ueki-san and Zang-san, have joined. Welcome aboard!