Unveiling the secret of
germline cells

Research Theme

Although individual animals do die, the species are maintained by sexual reproduction which give rises to next generation. Individuals are just like vehicles in which passenger –genetic information– can ride to be inherited to next generation through germline lineage. As such, germline cells are the most important cells to maintain the species. Drosophila melanogaster is one of the ideal model organisms where we can study gametogenesis. How are germline stem cells maintained in the microenvironment, niche? What is the molecular mechanism that controls germline cells to mature into egg and sperm? How germline genomes are safely guarded by non-coding RNA from transposons attacks? Our group has been addressing such molecular mechanisms for better understanding of gametogenesis.


A research paper by Prof. Kai is accepted in Nature Communications. Ryan Yee Wei Teo, Amit Anand, Vishweshwaren Sridhar, Katsutomo Okamura, Toshie Kai (2018) Role of Heterochromatin Protein 1a in pericentric and telomeric piRNA biogenesis in the Drosophila germline. Nature Commun. (in press)
A review article by Prof. Kai was published in GENETICS as a part of FLY BOOK. Ryan J. Gleason, Amit Anand, Toshie Kai*, Xin Chen* (2018) Protecting and diversifying the germline. GENETICS 208(2):435–471 *Co-corresponding
Prof Kai gave a special lecture to Ibaragi high school students!
Prof. Kai gave a career path talk in English at FBS.
New PhD students, Ueki-san and Zang-san, have joined. Welcome aboard!
A research paper by Dr. Iki (Assistant Professor) is published in RNA (Journal). Taichiro Iki, Marie-Aude Tschopp and Olivier Voinnet (2017) Biochemical and genetic functional dissection of the P38 viral suppressor of RNA silencing. RNA
We had a joint year-end party! Thanks for yummy oyster hot-pot!
A review paper by Dr. Iki (Assistant Professor) is published. Taichiro Iki (2017) Messages on small RNA duplexes in plants. J. Plant Res. 130:7–16
Prof. Kai made a talk at the workshop organized by the Faculty of Science.