Soft Biosystem Group


249. Yasuhara N, Yamagishi R, Arai Y, Mehmood R, Kimoto C, Fujita T, Touma K, Kaneko A, Kamikawa Y, Moriyama T, Yanagida T, Kaneko H, Yoneda Y. "Importin alpha subtypes determine differential transcription factor localization in embryonic stem cells maintenance.", Dev Cell., (2013) [PUBMED]

248. Kong SG, Arai Y, Suetsugu N, Yanagida T, Wada M. "Rapid severing and motility of chloroplast-actin filaments are required for the chloroplast avoidance response in Arabidopsis.", Plant Cell., (2013) [PUBMED]

247. Ikezaki K, Komori T, Yanagida T. "Spontaneous Detachment of the Leading Head Contributes to Myosin VI Backward Steps.", PLoS One., (2013) [PUBMED]


246. Morimatsu M, Togashi Y, Nishikawa S, Sugawa M, Iwane AH, Yanagida T. "Spontaneous structural changes in actin regulate G-F transformation.", PLoS One., (2012) [PUBMED]

245. Düttmann M, Mittnenzweig M, Togashi Y, Yanagida T, Mikhailov AS. "Complex Intramolecular Mechanics of G-actin - An Elastic Network Study.", PLoS One., (2012) [PUBMED]

244. Marcucci L, Yanagida T. "From Single Molecule Fluctuations to Muscle Contraction: A Brownian Model of A.F. Huxley's Hypotheses", PLoS One., (2012) [PUBMED]

243. M. Iwaki, L. Marcucci, Y. Togashi, T. Yanagida. "Single molecule and collective dynamics of motor proteins coupled with mechano-sensitive chemical reaction", Engineering chemical complexity, (In press), (2012)

242. K. Fujita, M. Iwaki, A. H. Iwane, L. Marcucci, T. Yanagida "Switching of myosin-V motion between the lever-arm swing and Brownian search-and-catch", Nat. Commun., (2012) [PUBMED]

241. T.Q.P. Noguchi, T. Komori, N. Umeki, N. Demizu, K. Ito, A. H. Iwane, K. Tokuraku, T. Yanagida, T.Q.P. Uyeda "SG146V mutation at the hinge region of actin reveals a myosin class-specific requirement of actin conformations for motility", J. Bio. Chem.,(2012) [PUBMED]

240. K. Ikezaki, T. Komori, M. Sugawa, Y. Arai, S. Nishikawa, A. H. Iwane, T. Yanagida. "Simultaneous Observation of the Lever Arm and Head Explains Myosin VI Dual Function", Small, (2012) [PUBMED]

239. Takahashi M, Shibata T, Yanagida T, Sako Y. "A protein switch with tunable steepness reconstructed in Escherichia coli cells with eukaryotic signaling proteins.", Biochem Biophys Res Commun., (2012) [PUBMED]

238. Ohmachi M, Komori Y, Iwane AH, Fujii F, Jin T, Yanagida T. "Fluorescence microscopy for simultaneous observation of 3D orientation and movement and its application to quantum rod-tagged myosin V.", Proc Natl Acad Sci U S A., (2012) [PUBMED]

237. Matsuoka S, Miyanaga Y, Yanagida T, Ueda M, "Visualizing single molecules in living Dictyostelium cells using total internal reflection fluorescent microscopy (TIRFM)., (2012) [PUBMED]

236. Matsuoka S, Miyanaga Y, Yanagida T, Ueda M, "Preparation of an imaging chamber for visualizing single molecules in living Dictyostelium cells.", Cold Spring Harb Protoc., (2012) [PUBMED]

235. Matsuoka S, Miyanaga Y, Yanagida T, Ueda M, "Preparation of chemotactically competent Dictyostelium cells.", Cold Spring Harb Protoc., (2012) [PUBMED]

234. Matsuoka S, Miyanaga Y, Yanagida T, Ueda M, "Single-molecule imaging of stochastic signaling events in living cells.", Cold Spring Harb Protoc., (2012) [PUBMED]

233. Düttmann M, Togashi Y, Yanagida T, Mikhailov AS, "Myosin-V as a mechanical sensor: an elastic network study.", Biophys J., ,(2012) [PUBMED]


232. Yanagida T, "Single molecule meets brain: a new concept to understand complex bio-system.", Rinsho Shinkeigaku. [Japanese], (2011) [PUBMED]

231. Hirano M, Onishi Y, Yanagida T, Ide T. "Role of the KcsA channel cytoplasmic domain in pH-dependent gating.", Biophys J., (2011) [PUBMED]

230. Kayo Hibino, Tatsuo Shibata, Toshio Yanagida, and Yasushi Sako, "Activation kinetics of RAF in the ternary complex of RAF, RASGTP, and kinase on the plasma membrane of living cells: single-molecule imaging analysis.", J Biol Chem., (2011) [PUBMED]

229. Mitsunori Kitta, Toru Ide, Minako Hirano, Hiroyuki Tanaka, Toshio Yanagida, and Tomoji Kawai, "Direct Manipulation of a Single Potassium Channel Gate with an Atomic Force Microscope Probe.", Small., 7,(2011) [PUBMED]


228. T. Ide, "Simultaneous optical and electronical recording of single molecule binding to single chennel proteins.", ChemPhysChem., 11, 3408-11 (2010) [PUBMED]

227. T.M. Watanabe, A.H. Iwane, H. Tanaka, M. Ikebe, T. Yanagida, "Mechanical characterization of one-headed myosin-V using optical tweezers.", PLoS One, 5, e12224 (2010) [PUBMED]

226. T.M. Watanabe, S. Fukui, T. Jin, F. Fujii, T. Yanagida, "Real-time Nanoscopy by using Blinking Enhanced Quantum Dots", Biophys. J., 99, L50-2 (2010) [PUBMED]

225. H. Fujita, H. Hatakeyama, T.M. Watanabe, M. Sato, H. Higuchi, M. Kanzaki, "Identification of Three Distinct Functional Sites of Insulin-mediated GLUT4 Trafficking in Adipocytes Using Quantitative Single Molecule Imaging.", Mo. Biol. Chem., 21, 2721-31 (2010) [PUBMED]

224. T.M. Watanabe, H. Tokuo, K. Gonda, H. Higuchi, M. Ikebe, "Dynamics of myosin-X during filopodia protrusion ", J Biol Chem, 285, 19605-14 (2010)

223. K. Gonda, T.M. Watanabe, N. Ouchi, H. Higuchi, "In Vivo nano-imaging of membrane dynamics in metastatic tumor cells using quantum dots", J Biol Chem, 285, 2750-57 (2010)

222. K. Amano, T. Yoshidome, M. Iwaki, M. Suzuki, M. Kinoshita, "Entropic potential field formed for a linear-motor protein near a filament: Statistical mechanical analyses using simple models.", The Journal of Chemical Physics, 133, 045103 (2010) [PUBMED]

221. S. Nishikawa, I. Arimoto, K. Ikezaki, M. Sugawa, H. Ueno, T. Komori, A. H Iwane, T. Yanagida., "Switch between large hand-over-hand and small inchworm-like steps in myosin VI", Cell, 142, 879-88 (2010) [PUBMED]

220. T. Fujii, A.H. Iwane, T. Yanagida, K. Namba., "Direct visualization of secondary structures of F-actin by electron cryomicroscopy.", Nature, 467, 724-8 (2010)[PUBMED]

219. Y. Arai, T. Shibata, S. Matsuoka, M. J. Sato, T. Yanagida, M. Ueda, "Self-organization of the phosphatidylinositol lipids signaling for random cell migration.", Proc. Natl. Acad. Sci. USA, 107, 12399-404 (2010) [PUBMED]

218. T.M. Watanabe, T. Yanagida, A.H. Iwane, "Single molecular observation of self-regulated kinesin motility.", Biochemistry, 49, 4654-61 (2010) [PUBMED]

217. Y. Togashi, T. Yanagida, A.S. Mikhailov, "Nonlinearity of Mechanochemical Motions in Motor proteins", PLoS Comput. Biol., 6, e1000814 (2010)[PUBMED]

216. H. Ueno, S. Nishikawa, R. Iino, K.V. Tabata, S. Sakakihara, T. Yanagida, H. Noji , "Simple dark-field microscopy with nanometer spatial precision and microsecond temporal resolution.", Biophys. J.98, 2014-23 (2010) [PUBMED]

215. Y. Tsuchiya, T. Komori, M. Hirano, T. Shiraki, A. Kakugo, T. Ide, J, -P. Gong, S. Yamada, T. Yanagida, S. Shinkai, "A Polysaccharide-Based Container Transportaion System Powered by Molecular Motors", Angew. Chem. Int. Ed. , 49, 724-7 (2010) [DOI]

214. M. Yamada, S. Toba, T. Takitoh, Y. Yoshida, D. Mori, T. Nakamura, A.H. Iwane, T. Yanagida, H. Imai, L.Y. Yu-Lee, T. Schroer, A. Wynshaw-Boris, S. Hirotsune, "mNUDC is required for plus-end-directed transport of cytoplasmic dynein and dynactins by kinesin-1", EMBO J., 29, 517-31 (2010) [PUBMED]

213. M. Sugawa,S. Nishikawa, A. H. Iwane, V. Biju, T. Yanagida, "Single-Molecule FRET imaging for Enzymatic Reactions at High Ligand Concentrations", Small, 6, 346-50 (2010) [PUBMED]

212. T. Ide, Y. Takeuchi, H. Noji, K. Tabata, "Simultaneous optical and electrical single channel recordings on aPEG glass", Langmuir, 26, 8540-3 (2010) [PUBMED]

211. M. Hirano, Y. Takeuchi, T. Aoki, T. Yanagida, T. Ide, "Rearrangements in the KcsA cytoplasmic domain underlie its gaiting.", J.Biol. Chem., 285, 3777-83 (2010) [PUBMED]


210. A. H. Iwane, M. Morimatsu, T. Yanagida, "Recombinant α-actin for specific fluorescent labeling", Proc. Jpn. Acad., Ser. B, 85, 491-9 (2009) [JSTAGE]

211. T. Ide, Y. Takeuchi, H. Noji, K. Tabata, "Simultaneous optical and electrical single channel recordings on aPEG glass", Langmuir, in press (2009)

209. K. V. Tabata, K. Sato, T. Ide, T. Nishizaka, A. Nakano, H.Noji, "Visualization of carge concentration by COPII minimal machinery in a plannar lipid membrane.", EMBO J., 28, 3279-89 (2009) [PUBMED]

208. Y. Miyanaga, S. Matsuoka, M. Ueda, "Single-molecule imaging techniques to visualize chemotactic signaling events on the membrane of living Dictyostelium cells.", Methods Mol. Biol., 571, 417-35 (2009) [PUBMED]

207. S. Matsuoka, T. Shibata, M. Ueda, Statistical analysis of lateral diffusion and multi-state kinetics in single-molecule imaging, Biophys. J., 97(4), 1115-1124 (2009) [PUBMED]

206. M. Iwaki, A. H. Iwane, T. Shimokawa, R. Cooke, T. Yanagida, Brownian search-and-catch mechanism for myosin-VI steps, Nat. Chem. Biol., 5(6), 403-405 (2009) [PUBMED]

205. M. Hirano, Y. Takeuchi, T. Aoki, T. Yanagida, T. Ide, Current recordings of ion channel proteins immobilized on resin beads, Anal. Chem., 81(8), 3151-3154 (2009) [PUBMED]

204. M. J. Sato, H. Kuwayama, W. N. van Egmond, A. L. K. Takayama, H. Takagi, P. J. M. van Haastert, T. Yanagida, M. Ueda, Switching direction in electric-signal-induced cell migration by cyclic guanosine monophosphate and phosphatidylinositol signaling, Proc. Natl. Acad. Sci. USA, 106(16), 6667-6672 (2009) [PUBMED]

203. S. I. Nishimura, M. Ueda, M. Sasai, Cortical factor feedback model for cellular locomotion and cytofission, PLoS Comput. Biol., 5(3), e1000310 (2009) [PUBMED]

202. T. Komori, S. Nishikawa, T. Ariga, A. H. Iwane, T. Yanagida, Simultaneous measurement of nucleotide occupancy and mechanical displacement in myosin-V, a processive molecular motor, Biophys. J., 96(1), L04-06 (2009) [PUBMED]


201. T. Ide, T. Kobayashi, M. Hirano, Lipid Bilayers at the Gel Interface for Single Ion Channel Recordings, Anal. Chem., 80(20), 7792-7795 (2008) [PUBMED]

200. Y. Maeda, T. Ide, M. Koike, Y. Uchiyama, T. Kinoshita, GPHR is a novel anion channel critical for acidification and functions of the Golgi apparatus, Nat. Cell Biol., 10(10), 1135-1145 (2008) [PUBMED]

199. K. Fujimoto, Y. Yoshimura, M. Ihara, K. Matsuda, Y. Takeuchi, T. Aoki, T. Ide, Cy3-3-Acylcholine: A Fluorescent Analogue of Acetylcholine for Single Molecule Detection, Bioorg. Med. Chem. Lett., 18(3), 1106-1109 (2008) [PUBMED]

198. Y. Taniguchi, T. Yanagida, The forward and backward stepping processes of kinesin are gated by ATP binding, Biophysics, 4, 11-18 (2008) [JSTAGE]

197. S. Yumura, M. Ueda, Y. Sako, T. Kitanishi-Yumura, T. Yanagida, Multiple mechanisms for accumulation of myosin II filaments at the equator during cytokinesis, Traffic, 9(12), 2089-2099 (2008) [DOI]

196. M. Nishikawa, H. Takagi, T. Shibata, A. H. Iwane, T. Yanagida, Fluctuation Analysis of Mechanochemical Coupling Depending on the Type of Biomolecular Motors, Phys. Rev. Lett., 101(12), 128103 (2008) [DOI]

195. M. Hirano, T. Kobayashi, T. Ide, Lipid Bilayers at Gel/Gel Interface for Ion Channel Recordings, e-J. Surf. Sci. Nanotech., 6, 130-133 (2008) [DOI]

194. T. Yanagida, M. Iwaki, Y. Ishii, Single molecule measurements and molecular motors, Phil. Trans. R. Soc. B, 363(1500), 2123-2134 (2008) [DOI]

193. T. Yanagida, H. Okano, A. Iriki, Introduction. Japan: its tradition and hot topics in biological sciences, Phil. Trans. R. Soc. B, 363(1500), 2067-2069 (2008) [DOI]

192. S. Miura, T. Shimokawa, T. Nomura, Stochastic simulations on a model of circadian rhythm generation, Biosystems, 93(1-2), 133-140 (2008) [DOI]

191. T. Shibata, M. Ueda, Noise generation, amplification and propagation in chemotactic signaling systems of living cells, Biosystems, 93(1-2), 126-132 (2008) [DOI]

190. T. Ariga, The concerted nature between three catalytic subunits driving the F1 rotary motor, Biosystems, 93(1-2), 68-77 (2008) [DOI]

189. K. Mouri, T. Shimokawa, The Fokker-Planck approach for the cooperative molecular motor model with finite number of motors, Biosystems, 93(1-2), 58-67 (2008) [DOI]

188. T. Komori, S. Nishikawa, T. Ariga, A. H. Iwane, T. Yanagida, Measurement system for simultaneous observation of myosin V chemical and mechanical events, Biosystems, 93(1-2), 48-57 (2008) [DOI]

187. M. Iwaki, A. H. Iwane, M. Ikebe, T. Yanagida, Biased Brownian motion mechanism for processivity and directionality of single-headed myosin-VI, Biosystems, 93(1-2), 39-47 (2008) [DOI]

186. Y. Ishii, Y. Taniguchi, M. Iwaki, T. Yanagida, Thermal fluctuations biased for directional motion in molecular motors, Biosystems, 93(1-2), 34-38 (2008) [DOI]

185. T. Yanagida, Fluctuation as a tool of biological molecular machines, Biosystems, 93(1-2), 3-7 (2008) [DOI]

184. H. Takagi, M. J. Sato, T. Yanagida, M. Ueda, Functional Analysis of Spontaneous Cell Movement under Different Physiological Conditions, PLoS ONE, 3(7), e2648 (2008) [DOI]

183. M. Ueda, M. Ueda, H. Takagi, M. J. Sato, T. Yanagida, I. Yamashita, K. Setsune, Biologically-inspired stochastic vector matching for noise-robust information processing, Physica A, 387(16-17), 4475-4481 (2008) [DOI]

182. A. Cressman, Y. Togashi, A. S. Mikhailov, R. Kapral, Mesoscale modeling of molecular machines: Cyclic dynamics and hydrodynamical fluctuations, Phys. Rev. E, 77(5), 050901 (2008) [DOI]

181. H. Kuwayama, T. Yanagida, M. Ueda, DNA oligonucleotide-assisted genetic manipulation increases transformation and homologous recombination efficiencies: Evidence from gene targeting of Dictyostelium discoideum, J. Biotech., 133(4), 418-423 (2008) [PUBMED]


180. Y. Takeuchi, T. Aoki, T. Yanagida, T. Ide, Immobilizing BK-channels in artificial lipid bilayers using annexin V, e-J. Surf. Sci. Nanotech., 5, 1-5 (2007) [DOI]

179. T. Miyauchi, T. Yanagida, Y. Sako, Rho small GTPase regulates the stability of individual focal adhesions: a FRET-based visualization of GDP/GTP exchange on small GTPases, Biophysics, 3, 63-73 (2007) [JSTAGE]

178. M. Morimatsu, H. Takagi, K. G. Ota, R. Iwamoto, T. Yanagida, Y. Sako, Multiple-state reactions between the epidermal growth factor receptor and Grb2 as observed by using single-molecule analysis, Proc. Natl. Acad. Sci. USA, 104(46), 18013-18018 (2007) [PUBMED]

177. S. Oka, J. D. Victor, M. M. Conte, T. Yanagida, VEPs elicited by local correlations and global symmetry: characteristics and interactions, Vision Res., 47(16), 2212-2222 (2007) [PUBMED]

176. Y. Komori, A. H. Iwane, T. Yanagida, Myosin-V makes two brownian 90 degrees rotations per 36-nm step, Nat. Struct. Mol. Biol., 14(10), 968-973 (2007) [PUBMED]

175. S. Kohno, I. Miyai, A. Seiyama, I. Oda, A. Ishikawa, S. Tsuneishi, T. Amita, K. Shimizu, Removal of the skin blood flow artifact in functional near-infrared spectroscopic imaging data through independent component analysis, J. Biomed. Opt., 12(6), 062111 (2007) [PUBMED]

174. V. V. Yakovlev, S. Nishikawa, T. Yanagida, Imaging of cooperative motion on a simulated energy landscape, Proc. SPIE "Nanoscale Imaging, Spectroscopy, Sensing and Actuation for Biomedical Applications IV", 6447-12, D1-D8 (2007) [DOI]

173. M. Ueda, T. Shibata, Stochastic signal processing and transduction in chemotactic response of eukaryotic cells, Biophys. J., 93(1), 11-20 (2007) [PUBMED]

172. S. Esaki, Y. Ishii, M. Nishikawa, T. Yanagida, Cooperative actions between myosin heads bring effective functions, Biosystems, 88(3), 293-300 (2007) [PUBMED]

171. T. Yanagida, M. Ueda, T. Murata, S. Esaki, Y. Ishii, Brownian motion, fluctuation and life, Biosystems, 88(3), 228-242 (2007) [PUBMED]

170. J. Kozuka, H. Yokota, Y. Arai, Y. Ishii, Y. Yanagida, Dynamic polymorphism of actin as activation mechanism for cell motility, Biosystems, 88(3), 273-282 (2007) [PUBMED]

169. M. Sugawa, Y. Arai, A. H. Iwane, Y. Ishii, Y. Yanagida, Single molecule FRET for the study on structural dynamics of biomolecules, Biosystems, 88(3), 243-250 (2007) [PUBMED]

168. Y. Miyanaga, S. Matsuoka, T. Yanagida, M. Ueda, Stochastic signal inputs for chemotactic response in Dictyostellium cells revealed by single molecule imaging techniques, Biosystems, 88(3), 251-260 (2007) [PUBMED]

167. Y. Taniguchi, P. Karagiannis, M. Nishiyama, Y. Ishii, T. Yanagida, Single molecule thermodynamics in biological motors, Biosystems, 88(3), 283-292 (2007) [PUBMED]

166. M. J. Sato, M. Ueda, H. Takagi, T. M. Watanabe, T. Yanagida, M. Ueda, Input-output relationship in galvanotactic response of Dictyostelium cells, Biosystems, 88(3), 261-272 (2007) [PUBMED]

165. Y. Tsukasaki, K. Kitamura, K. Shimizu, A. H. Iwane, Y. Takai, T. Yanagida, Role of Multiple Bonds Between the Single Cell Adhesion Molecules, Nectin and Cadherin, Revealed by High Sensitive Force Measurements, J. Mol. Biol., 357, 996-1006 (2007) [PUBMED]

164. T. Okada, H. Tanaka, A. H. Iwane, K. Kitamura, M. Ikebe, T. Yanagida, The diffusive search mechanism of processive myosin class-V motor involves directional steps along actin subunits, Biochem. Biophys. Res. Commun., 354, 379-384 (2007) [PUBMED]

163. A. J. Montgomery, P. Stokes, Y. Kitamura, P. M. Grasby, Extrastriatal D2 and striatal D2 receptors in depressive illness: Pilot PET studies using [11C]FLB 457 and [11C]raclopride, J. Affective Disorders, 101(1-3), 113-122 (2007) [DOI]

162. J-Y. Li, H. Ueda, A. Seiyama, J. Seki, K. Konaka, T. Yanagida, S. Sakoda, T. Yanagihara, Ischemic vasoconstriction and tissue energy metabolism during global cerebral ischemia in gerbils, J. Neurotrauma, 24(3), 547-558 (2007) [PUBMED]

161. G. Tajima, T. Shiozaki, A. Seiyama, T. Mohri, K. Kajino, H. Nakae, O. Tasaki, H. Ogura, Y. Kuwagata, H. Tanaka, T. Shimazu, H. Sugimoto, Mismatch Recovery of Regional Cerebral Blood Flow and Brain Temperature During Reperfusion After Prolonged Brain Ischemia in Gerbils, Journal of Trauma, 62(1), 36-43 (2007) [PUBMED]


160. Y. Saga, T. Wazawa, Y. Ishii, T. Yanagida, H. Tamiaki, Single supramolecule spectroscopy of natural and alkaline-treated chlorosomes from green sulfur photosynthetic bacteria, J. Nanosci. Nanotechnol., 6, 1750-7 (2006) [PUBMED]

159. S. Kobashi, Y. Kitamura, K. Kondo, Y. Hata, T. Yanagida, Language Laterality Index Regionally Specified with Fuzzy Logic Using Near-infrared Spectroscopy, J. JSFTS, 18(3), 414-424 (2006) [CiNii]

158. S. Tanaka, W. Fritzsche, Y. Sako, T. Yanagida, Synthesis of Long-Template DNA using Enzymatic Reactin and Regular Alignment of Au-nanoparticles, Chemistry Letters, 35(11), 1290-1291 (2006) [JSTAGE]

157. Y. Ooi, Y. Satomura, J. Seki, T. Yanagida, A. Seiyama, Optical coherence tomography revealed in vivo cortial plasticity of adult mice in response to peripheralneuropathic pain, Neurosci Letter, 397, 35-39 (2006) [PUBMED]

156. I. Sase, A. Takatsuki, J. Seki, T. Yanagida, A. Seiyama, Noncontact backscatter-mode near-infrared time-resolved imaging sstem: Primary study for functional brain mapping, J. Biomed. Opt, 11(5), 054006 (2006) [PUBMED]

155. Y. Teramura, J. Ichinose, H. Takagi, K. Nishida, T. Yanagida, Y. Sako, Single-molecule analysis of epidermal growth factor binding on the surface of living cells, EMBO J, 25, 4215-4222 (2006) [PUBMED]

154. J. Ichinose, M. Morimatsu, T. Yanagida, Y. Sako, Covalent immobilization of epidermal growth factor molecule for single-molecule imaging analysis of intracellular signaling, Biomaterials, 27, 3343-50 (2006) [PUBMED]

153. T. Ide, T. Aoki, Y. Takeuchi, T. Yanagida, Lysenin forms a voltage-dependent channel in artificial lipid bilayer membranes, Biochemical and Biophysical Research Communications, 346(1), 288-92 (2006) [PUBMED]

152. T. Ichikawa, T. Aoki, Y. Takeuchi, T. Yanagida, T. Ide, Immobilizing single lipid and channel molecules in artificial lipid bilayers with annexin A5, Langmuir, 22(14), 6302-6307 (2006) [PUBMED]

151. M. Nishikawa, S. Nishikawa, A. Inoue, A. H. Iwane, T. Yanagida, M. Ikebe, A unique mechanism for the processive movement of single-headed myosin-IX, Biochem Biophys Res Commun., 343(4), 1159-1164 (2006) [PUBMED]

150. Y. Arai, A. H. Iwane, T. Wazawa, H. Yokota, Y. Ishii, T. Kataoka, T. Yanagida, Dynamic polymorphism of Ras observed by single molecule FRET is the basis for molecular recognition, Biochem Biophys Res Commun., 343(3), 809-15 (2006) [PUBMED]

149. M. Iwaki, H. Tanaka, A. H. Iwane, E. Katayama, M. Ikebe, T. Yanagida, Cargo-Binding Makes a Wild-Type Single-Headed Myosin-VI Move Processively, Biophys J., 90(10), 3643-52 (2006) [PUBMED]

148. S. C. Shibata, K. Hibino, T. Mashimo, T. Yanagida, Y. Sako, Formation of signal transduction complexes during immobile phase of NGFR movements, Biochem Biophys Res Commun., 342, 316-22 (2006) [PUBMED]

147. J. Seki, Y. Satomura, Y. Ooi, T. Yanagida, A. Seiyama, Velocity profiles in the rat cerebral microvessels measured by optical coherence tomography, Clinical Hemorheology and Microcirculation, 34, 233-239 (2006) [PUBMED]

146. F. Vazquez, S. Matsuoka, W. R. Sellers, T. Yanagida, M. Ueda, P. N. Devreotes, Tumor suppressor PTEN acts through dynamic interaction with the plasma membrane, Proc. Natl. Acad. Sci. USA, 103(10), 3633-3638 (2006) [PUBMED]

145. S. Matsuoka, M. Iijima, T. M. Watanabe, H. Kuwayama, T. Yanagida, P. N. Devreotes, M. Ueda, Single-molecule analysis of chemoattractant-stimulated membrane recruitment of a PH domain-containing protein, Journal of Cell Science, 119, 1071-1079 (2006) [PUBMED]

144. J. Kozuka, H. Yokota, Y. Arai, Y. Ishii, T. Yanagida, Dynamic polymorphism of single actin molecules in the actin filament, Nature Chemical Biology, 2, 83-86 (2006) [PUBMED]

143. A. Seiyama, Virtual Cooperativity in Myoglobin Oxygen Saturation Curve in Skeletal Muscle In Vivo, Dynamic Medicine, 5(3), 1-8 (2006) [PUBMED]


142. T. Aoki, Y. Sowa, T. Ide, T. Yanagida, Non-contact surface force microscopy for molecular interaction study, e-J. Surf. Sci. Nanotech., 3, 46-50 (2005) [DOI]

141. Y. Hata, S. Kobayashi, K. Kondo, Y. Kitamura, T. Yanagida, Transcranial Ultrasonography System for Visualizing Skull and Brain Surface Aided by Fuzzy Expert System, IEEE Trans. Syst., Man, Cybern. B, 35(6), 1360-1373 (2005) [PUBMED]

140. H. Takagi, K. Kaneko, Dynamical systems basis of metamorphosis: diversity and plasticity of cellular states in reaction diffusion network, J. of Theor. Biol., 234(2), 173-186 (2005) [PUBMED]

139. Y. Inoue, A. Seiyama, H. Tanaka, I. Ukai, P. Akimau, M. Nishino, T. Shimadzu, H. Sugimoto, Protective effects of a selective neutrophil elastase inhibitor(sivelestat) on lipopolysaccharide-induced acute dysfunction of the pulmonary microcirculation, Critical Care Medicine, 33(8), 1814-1822 (2005) [PUBMED]

138. A. H. Iwane, H. Tanaka, S. Morimoto, A. Ishijima, T. Yanagida, The neck domain of myosin II primarily regulates the actomyosin kinetics, not the stepsize, J. Mol. Biol., 353, 213-221 (2005) [PUBMED]

137. Y. Taniguchi, M. Nishiyama, Y. Ishii, T. Yanagida, Entropy rectifies the Brownian steps of kinesin, Nature Chem. Biol., 1, 346-351 (2005) [PUBMED]

136. A. Seiyama, J. Seki, M. Iwamoto, T. Yanagida, Paramagnetic artifact and safety criteria for human brainmapping, Dynamic Medicine, 4(5), 1-4 (2005) [PUBMED]

135. T. Uyemura, H. Takagi, T. Yanagida, Y. Sako, Single-molecule analysis of epidermal growth factor signaling that leads to ultrasensitive calcium response, Biophys. J., 88(5), 3720-3730 (2005) [PUBMED]

134. T. Tani, Y. Miyamoto, K. Fujimori, T. Taguchi, T. Yanagida, Y. Sako, Y. Harada, Trafficking of a Ligand-Receptor Complex on the Growth Cones as an Essential Step for the Uptake of Nerve Growth Factor at the Distal End of the Axon: A Single-Molecule Analysis, The Journal of Neuroscience, 25(9), 2181-2191 (2005) [PUBMED]

133. K. Kitamura, M. Tokunaga, S. Esaki, A. Iwane, T. Yanagida, Mechanism of muscle contraction based on stochastic properties of single actomyosin motors observed in vitro, Biophysics, 1, 1-19 (2005) [JSTAGE]


132. J. Ichinose, M. Murata, T. Yanagida, Y. Sako, EGF Signalling Amplification Induced by Dynamic Clustering of EGFR, Biochemical and Biophysical Research Communications, 324, 1143-1149 (2004) [PUBMED]

131. H. Yokota, K. Kaseda, H. Matsuura, Y. Arai, A. Iwane, Y. Ishii, T. Kodama, T. Yanagida, Single-Molecule Imaging of the Dynamic Interactions between Macromolecules, Journal of Nanoscience and Nanotechnology, 4(6), 616-621 (2004) [PUBMED]

130. J. Ichinose, Y. Sako, Single-molecule measurement in living cells, Trends in Analytical Chemistry, 23(8), 587-594 (2004)

129. M. Ueda, Y. Miyanaga, T. Yanagida, Single-molecule analysis of chemotactic signaling mediated by cAMP receptors on living cells, CMC Methods in signal transduction series "G Protein-Coupled Receptors: Structure, Function and Ligand Screening", in press (2004)

128. M. Y. Ali, K. Homma, A. H. Iwane, K. Adachi, H. Itoh, K. Kinoshita, T. Yanagida, M. Ikebe, Unconstrained steps of myosin VI appear longest among known molecular motors, Biophys. J., 86, 3804-3810 (2004) [PUBMED]

127. T. M. Watanabe, H. Tanaka, A. H. Iwane, S. M. Yonekura, K. Homma, A. Inoue, R. Ikebe, T. Yanagida, M. Ikebe, A one-head myosin-V molecule develops multiple large (`32nm) steps successively, Proc. Natl. Acad. Sci. USA, 101, 9630-9635 (2004) [PUBMED]

126. Y. Ishii, M. Nishiyama, T. Yanagida, Mechano-chemical coupling of molecular motors revealed by single molecule measurements, Curr Protein Pept Sci., 5, 81-87 (2004) [PUBMED]

125. Y. Satomura, J. Seki, Y. Ooi, T. Yanagida, A. Seiyama, In vivo imaging of the rat cerebral microvessels with optical coherence tomography, Clinical Hemorheology and Microcirculation, 31, 31-40 (2004) [PUBMED]

124. T. Higashi, Y. Sone, K. Ogawa, Y. T. Kitamura, K. Saiki, S. Sagawa, T. Yanagida, A. Seiyama, Changes in regional cerebral blood volume in frontal cortex during mental work with and without caffeine intake: Functional monitoring using near-infrared spectroscopy, Journal of Biomedical Optics, 9(4), 788-793 (2004) [PUBMED]

123. A. Takatsuki, H. Eda, T. Yanagida, A. Seiyama, Absorber's Effect Projected Directly Above Improves Spatial Resolution in Near Infrared Backscattered Imaging, Jpn J Physiol., 54, 79-86 (2004) [PUBMED]

122. A. Seiyama, J. Seki, H. C. Tanabe, I. Sase, A. Takatsuki, S. Miyauchi, H. Eda, S. Hayashi, T. Imaruoka, T. Iwakura, T. Yanagida, Circulatory basis of fMRI signals: Relationship between changes in the hemodynamic parameters and BOLD signal intensity, NeuroImage, 21, 1204-1214 (2004) [PUBMED]


121. M. Ikebe, A. Inoue, S. Nishikawa, K. Homma, H. Tanaka, A. H. Iwane, E. Katayama, R. Ikebe, T. Yanagida, Motor function of unconventional myosin, Adv. Exp. Med. Biol., 538, 143-156 (2003) [PUBMED]

120. A. Seiyama, J. Seki, H. C. Tanabe, Y. Ooi, Y. Satomura, H. Fujisaki, T. Yanagida, Regulation of oxygen transport during brain activation: stimulus-induced hemodynamic responses in human and animal cortices, Dynamic Medicine, 20(6), 1-10 (2003) [PUBMED]

119. T. Aoki, Y. Sowa, T. Yanagida, Noncontact surface force microscopy of protein molecules, Chemphyschem., 15, 1361-1364 (2003) [PUBMED]

118. G. Yao, X. Fang, H. Yokota, T. Yanagida, W. Tan, Monitoring molecular beacon DNA probe hybridization at the single-molecule level, Chemistry, 9, 5686-5692 (2003) [PUBMED]

117. T. Murai, Y. Miyazaki, H. Nishinakamura, K. N. Sugahara, T. Miyauchi, Y. Sako, T. Yanagida, M. Miyasaka, Engagement of CD44 Promotes Rac Activation and CD44 Cleavage during Tumor Cell Migration, J Biol Chem., 279, 4541-4550 (2003) [PUBMED]

116. Y. Sako, T. Yanagida, Single-molecule visualization in cell biology, Nat Rev Mol Cell Biol., 4, SS1-SS5 (2003) [PUBMED]

115. T. Yanagida, Y. Ishii, Stochastic processes in nano-biomachines revealed by single molecule detection, Biosystems, 71, 233-244 (2003) [PUBMED]

114. K. Kitamura, T. Yanagida, Stochastic properties of actomyosin motor, Biosystems, 71, 101-110 (2003) [PUBMED]

113. T. Murata, N. Matsui, S. Miyauchi, Y. Kakita, T. Yanagida, Discrete stochastic process underlying perceptual rivalry, Neuroreport, 14, 1347-1352 (2003) [PUBMED]

112. T. Imaruoka, T. Yanagida, S. Miyauchi, Attentional set for external information activates the right intraparietal area, Brain Res Cogn Brain Res., 16, 199-209 (2003) [PUBMED]

111. Y. Ishii, K. Kitamura, H. Tanaka, T. Yanagida, Molecular motors and single-molecule enzymology, Methods Enzymol., 361, 228-245 (2003) [PUBMED]

110. M. Nishiyama, H. Higuchi, Y. Ishii, Y. Taniguchi, T. Yanagida, Single molecule processes on the stepwise movement of ATP-driven molecular motors, Biosystems, 71, 147-158 (2003) [PUBMED]

109. K. Hibino, T. M. Watanabe, J. Kozuka, A. H. Iwane, T. Okada, T. Kataoka, T. Yanagida, Y. Sako, Single- and multiple-molecule dynamics of the signaling from H-Ras to cRaf-1 visualized on the plasma membrane of living cells, CHEMPHYSCHEM, 4, 748-753 (2003) [PUBMED]

108. S. Esaki, Y. Ishii, T. Yanagida, Model describing the biased Brownian movement of myosin, Proc. Japan Acad., 79, 9-14 (2003)


107. Y. Ishii, T. Yanagida, A new view concerning an actomyosin motor, Cell Mol Life Sci., 59, 1767-1770 (2002) [PUBMED]

106. T. Ide, Y. Takeuchi, T. Aoki, T. Yanagida, Simultaneous optical and electrical recording of a single ion-channel, Jpn J Physiol., 52, 429-434 (2002) [PUBMED]

105. M. Nishiyama, H. Higuchi, T. Yanagida, Chemomechanical coupling of the ATPase cycle to the forward and backward movements of single kinesin molecules, Nature Cell Biology, 4, 790-797 (2002) [PUBMED]

104. T. Ide, Y. Takeuchi, T. Yanagida, Development of an Experimental Apparatus for Simultaneous Observation of Optical and Electrical Signals from Single Ion Channels, Single Molecules, 3, 33-42 (2002)

103. Y. Saga, T. Wazawa, T. Mizoguchi, Y. Ishii, T. Yanagida, H. Tamiaki, Spectral Heterogeneity in Single Light-Harvesting Chlorosomes from Green Sulfur Photosynthetic Bacterium Chlorobium tepidum, Photochem. Photobiol., 75(4), 433-436 (2002) [PUBMED]

102. S. Nishikawa, K. Homma, Y. Komori, M. Iwaki, T. Wazawa, A. H. Iwane, J. Saito, R. Ikebe, E. Katayama, T. Yanagida, M. Ikebe, Class VI myosin moves processively along actin filament backwards with large steps, Biochem. Biophys. Res. Commun., 290, 311-317 (2002) [PUBMED]

101. H. Tanaka, K. Homma, A. H. Iwane, E. Katayama, R. Ikebe, J. Saito, T. Yanagida, M. Ikebe, The motor domain determines the large step of myosin-V, Nature, 415, 192-195 (2002) [PUBMED]

100. Y. Saga, T. Wazawa, T. Nakada, Y. Ishii, T. Yanagida, H. Tamiaki, Fluorescence Emission Spectroscopy of Single Light-Harvesting Complex from Green Filamentous Photosynthetic Bacteria, J. Phys. Chem. B., 106, 1430-1433 (2002) [PUBMED]

99. Y. Ishii, A. Ishijima, T. Yanagida, "Coupling between Chemical and Mechanical Events and Conformation of Single Protein Molecules", Molecular Interactions of Actin: Myosin interaction, motility assays and Ca-Regulatory proteins (D. D. Thomas and C. G. dos Remedios eds.) Springer Verlag (Heidelberg), 36, 87-105 (2002) [PUBMED]


98. M. Ueda, Y. Sako, T. Tanaka, P. Devreotes, T. Yanagida, "Single molecule analysis of chemotactic signaling in Dictyostelium cells", Science, 294, 864-867 (2001) [PUBMED]

97. T. Aoki, Y. Sowa, H. Yokota, M. Hiroshima, M. Tokunaga, Y. Ishii, T. Yanagida, "Non-Contact Electrostatic Surface Force Imaging of Single Protein Filaments using Intermolecular Force Microscopy", Single Mol., 3, 183-190 (2001)

96. Y. Inoue, A. H. Iwane, T. Miyai, E. Muto, T. Yanagida, Motility of single one-headed kinesin molecules along microtubules, Biophysical Journal, 81, 2838-2850 (2001) [PUBMED]

95. A. Ishijima, T. Yanagida, Single Molecule Nano-Bioscience, Trends in Biochemical Sciences, 26, 438-444 (2001)

94. Y. Ishii, A. Ishijima, T. Yanagida, Single molecule nanomanipulation of bio molecule, Trends in Biotechnology, 19, 211-216 (2001) [PUBMED]

93. M. Nishiyama, E. Muto, Y. Inoue, T. Yanagida, H. Higuchi, Substeps within the 8-nm step of the ATPase cycle of single kinesin molecules, Nature Cell Biology, 3, 425-428 (2001) [PUBMED]


92. T. Yanagida, H. Tanaka, K. Kitamura, T. Wazawa, M. Nishiyama, S. Esaki, Y. Sako, T. Ide, A. H. Iwane, Y. Ishii, Single molecule techniques in biophysics, Na/K-ATPase and Related ATPases (K. Taniguchi and S. Kaya eds.) ELSEVIER, 71-85 (2000)

91. S. Kobashi, Y. Hata, M. Ishikawa, Y. Kitamura, T. Yanagida, Medical image registration based on fuzzy and multiple-valued logics, Proc. Second Int. Forum on Multimedia and Image Processing (IFMIP-067, CDROM), 270-275 (2000)

90. S. Kobashi, Y. Hata, Y. Kitamura, T. Yanagida, A Fuzzy Rule-Based Region Growing Method for Segmenting 3-D Dynamic MR Images, J Biomed. Fuzzy Systems Assoc., 6(1), 85-94 (2000) [CiNii]

89. F. Kano, Y. Sako, M. Tagaya, T. Yanagida, M. Murata, Reconstitution of brefeldin A-induced Golgi-tubulation and its fusion with the ER in semi-intact CHO cells, Mol. Biol. Cell., 11, 3073-3087 (2000) [PUBMED]

88. Y. Sako, K. Hibino, T. Miyauchi, Y. Miyamoto, M. Ueda, T. Yanagida, Single-Molecule Imaging of Signaling Molecules in Living Cells, Single Molecules, 1, 159-163 (2000)

87. T. Yanagida, A. H. Iwane, A large step for myosin, Proc. Natl. Acad. Sci. USA, 97, 9357-9359 (2000) [PUBMED]

86. S. Shimizu, T. Ide, T. Yanagida, Y. Tsujimoto, Electrophysiological Study of a Novel Large Pore Formed by Bax and the Voltage-dependent Anion Channel That Is Permeable to Cytochrome c, J. Biological Chemistry, 275, 12321-12325 (2000) [PUBMED]

85. Y. Ishii, Y. Kimura, K. Kitamura, H. Tanaka, T. Wazawa, T. Yanagida, Imaging and Nano-manipulation of Single Actomyosin Motors at Work, Clinical and Experimental Pharmacology and Physiology, 27, 229-237 (2000) [PUBMED]

84. Y. Sako, S. Minoguchi, T. Yanagida, Single-molecule imaging of EGFR signalling on the surface of living cells, Nature Cell Biology, 2, 168-172 (2000) [PUBMED]

83. K. Kaseda, H. Yokota, Y. Ishii, T. Yanagida, T. Inoue, K. Fukui, T. Kodama, Single-molecule imaging of interaction between dextran and glucosyltransferase from streptococcus sobrinus, Journal of Bacteriology, 182, 1162-1166 (2000) [PUBMED]

82. T. Wazawa, Y. Ishii, T. Funatsu, T. Yanagida, Spectral fluctuation of a single fluorophore conjugated to a protein molecule, Biophys. J., 78, 1561-1569 (2000) [PUBMED]

81. T. Yanagida, S. Esaki, A. H. Iwane, Y. Inoue, A. Ishijima, K. Kitamura, H. Tanaka, M. Tokunaga, Single-motor mechanics and models of the myosin motor, The Royal Society Philosophical Transactions B, 355, 1-7 (2000) [PUBMED]

80. T. Yanagida, K. Kitamura, H. Tanaka, A. H. Iwane, S. Esaki, Single molecule analysis of the actomyosin motor, Current Opinion in Cell Biology, 12, 20-25 (2000) [PUBMED]

79. Y. Ishii, T. Yanagida, Single Molecule Detection in Life Science, Single Molecules, 1, 5-14 (2000)

78. Y. Miyamoto, E. Muto, T. Mashimo, A. H. Iwane, I. Yoshiya, T. Yanagida, Direct Inhibition of Microtubule-based Kinesin Motility by Local Anesthetics, Biophys. J., 78, 940-949 (2000) [PUBMED]


77. R. Yamasaki, M. Hoshino, T. Wazawa, Y. Ishii, T. Yanagida, Y. Kawata, T. Higurashi, K. Sakai, J. Nagai, Y. Goto, Single Molecular Observation of the Interaction of GroEL with Substrate Proteins, J. Mol. Biol., 292, 965-972 (1999)

76. Y. Sambongi, Y. Iko, M. Tanabe, H. Omote, A. Iwamoto-Kihara, I. Ueda, T. Yanagida, Y. Wada, M. Futai, Mechanical Rotation of the c Subunit Oligomer in the ATP Synthase (FoF1): Direct Observation, Science, 286, 1722-1724 (1999)

75. T. Ide, T. Yanagida, An artificial lipid bilayer formed on an agarose-coated glass for simultaneous electrical and optical measurement of single ion-channels, Biochem. Biophys. Res. Commun., 265, 595-599 (1999) [PUBMED]

74. H. Omote, N. Sambonmatsu, K. Saito, Y. Sambongi, A. I. Kihara, T. Yanagida, Y. Wada, M. Futai, The γ subunit rotation and torque generation in F1-ATPase from wild-type or uncoupled mutant Escherichia coli, Proc. Natl. Acad. Sci. USA., 96, 7780-7784 (1999)

73. S. Iwatani, A. H. Iwane, H. Higuchi, Y. Ishii, T. Yanagida, Mechanical and Chemical Properties of Cysteine-Modified Kinesin Molecules, Biochemistry, 38, 10318-10323 (1999) [PUBMED]

72. Y. Ishii, T. Yoshida, T. Funatsu, T. Wazawa, T. Yanagida, Fluorescence resonance energy transfer between single fluorophores attached to a coiled-coil protein in aqueous solution, Chemical Physics, 247, 163-173 (1999)

71. Y. Harada, T. Funatsu, K. Murakami, Y. Nonoyama, A. Ishihama, T. Yanagida, Single molecule imaging of RNA polymerase-DNA interactions in real time, Biophys. J., 76, 709-715 (1999) [PUBMED]

70. K. Kitamura, M. Tokunaga, A. H. Iwane, T. Yanagida, A single myosin head moves along an actin filament with regular steps of ~5.3nm, Nature, 397, 129-134 (1999) [PUBMED]

69. X. Liu, K. Ito, S. Morimoto, A. H. Iwane, T. Yanagida, T. Q. P. Uyeda, Filament structure as an essential factor for regulation of Dictyostelium myosin by regulatory light chain phosphorylation, Proc. Natl. Acad. Sci. USA, 95, 14124-14129 (1998)

68. H. Tanaka, A. Ishijima, M. Honda, K. Saito, T. Yanagida, Orientation dependence of displacements by a single one-headed myosin relative to the actin filament, Biophys. J., 75, 1886-1894 (1998) [PUBMED]

67. H. Yokota, K. Saito, T. Yanagida, Single molecule imaging of fluorescently-labeled proteins on metal by surface plasmons in aqueous solution, Phys. Rev. Lett., 80(20), 4606-4609 (1998)

66. C. Shingyoji, H. Higuchi, M. Yoshimura, E. Katayama, T. Yanagida, Dynein arms are oscillating force generators, Nature, 393, 711-714 (1998) [PUBMED]

65. A. Ishijima, H. Kojima, T. Funatsu, M. Tokunaga, H. Higuchi, H. Tanaka, T. Yanagida, Simultaneous observation of individual ATPase and mechanical events by a single myosin molecule during interation with actin, Cell, 92, 161-171 (1998) [PUBMED]

64. T. Aoki, M. Hiroshima, K. Kitamura, M. Tokunaga, T. Yanagida, Non-contract scanning probe microscopy with sub-piconewton force sensitivity, Ultramicroscopy, 70, 45-55 (1997)

63. K. Saito, M. Tokunaga, A. H. Iwane, T. Yanagida, Dual-colour microscopy of single fluorophores bound to myosin interacting with fluorescently labelled actin using anti-stoke fluorescence, J. Microscopy, 188, 255-263 (1997) [PUBMED]

62. T. Funatsu, Y. Harada, H. Higuchi, M. Tokunaga, K. Saito, Y. Ishii, R. D. Vale, T. Yanagida, Imaging and nano-manipulation of single biomolecules, Biophysical Chemistry, 68, 63-72 (1997) [PUBMED]

61. Y. Harada, T. Funatsu, M. Tokunaga, K. Saito, H. Higuchi, Y. Ishii, T. Yanagida, Single molecule imaging and nano-manipulation of biomolecules, Method in Cell Biology (M. P. Sheetz eds.) Academic Press, 55, 117-128 (1997) [PUBMED]

60. H. Kojima, E. Muto, H. Higuchi, T. Yanagida, Mechanics of single kinesin molecules measured by optical trapping nanometry, Biophys. J., 73, 2012-2022 (1997) [PUBMED]

59. M. Tokunaga, K. Kitamura, K. Saito, A. Hikikoshi Iwane, T. Yanagida, Single molecule imaging of fluorophores and enzymatic reactions achieved by objective-type total internal reflection fluorescence microscopy, Biochem. Biophys. Res. Commun., 235, 47-53 (1997) [PUBMED]

58. Y. Inoue, Y. Yano-Toyoshima, A. Hikikoshi-Iwane, S. Morimoto, H. Higuchi, T. Yanagida, Movements of truncated kinesin fragments with a short or an artificial flexible neck, Proc. Natl. Acad. Sci. USA, 94, 7275-7280 (1997) [PUBMED]

57. H. Higuchi, E. Mutoh, Y. Inoue, T. Yanagida, Kinetics of force generation by single kinesin molecules activated by laser photolysis of caged ATP, Proc. Natl. Acad. Sci. USA, 94, 4395-4400 (1997) [PUBMED]

56. A. Hikikoshi Iwane, T. Funatsu, Y. Harada, M. Tokunaga, O. Ohara, S. Morimoto, T. Yanagida, Single molecular assay of individual ATP turnovers by a myosin-GFP fusion protein expressed in vitro, FEBS Letters, 407, 235-238 (1997) [PUBMED]

55. M. Tokunaga, T. Aoki, M. Hiroshima, K. Kitamura, T. Yanagida, Subpiconewton intermolecular force microscopy, Biochem. Biophys. Res. Commun., 231, 566-569 (1997) [PUBMED]

54. A. Hikikoshi Iwane, K. Kitamura, M. Tokunaga, T. Yanagida, Myosin subfragment-1 is fully equipped with factors essential for motor function, Biochem. Biophys. Res. Commun., 230, 76-80 (1997) [PUBMED]

53. M. Suzuki, J. Shigematsu, Y. Fukunishi, Y. Harada, T. Yanagida, T. Kodama, Coupling of protein surface hydrophobicity change to ATP hydrolysis by myosin motor domain, Biophys. J., 72, 18-23 (1997) [PUBMED]

52. J. West, H. Higuchi, A. Ishijima, T. Yanagida, Modification of the bi-directional sliding movement of actin filaments along native thick filaments isolated from a clam, J. Muscle Res. and Cell Motility, 17, 637-646 (1996) [PUBMED]

51. Y. Tsuda, T. Mashimo, I. Yoshiya, K. Kaseda, Y. Harada, T. Yanagida, Direct inhibition of the actomyosin motility by local anesthetics in vitro, Biophys. J., 71, 2733-2741 (1996) [PUBMED]

50. Y. Tsuda, H. Yasutake, A. Ishijima, T. Yanagida, Torsional rigidity of single actin filaments and actin-actin bond breaking force under torsion measured directly by in vitro micromanipulation, Proc. Natl. Acad. Sci. USA, 93, 12937-12942 (1996) [PUBMED]

49. R. D. Vale, T. Funatsu, D. W. Pierce, L. Romberg, Y. Harada, T. Yanagida, Direct observation of single kinesin molecules moving along microtubules, Nature, 380, 451-453 (1996) [PUBMED]

48. A. Ishijima, H. Kojima, H. Higuchi, Y. Harada, T. Funatsu, T. Yanagida, Multiple-and-Single-molecule analysis of the actomyosin motor using nanometer-piconewton manipulation with a microneedle: Unitary step and force, Biophys. J., 70, 383-400 (1996) [PUBMED]

47. M. Irisa, A. Kidera, H. Nakamura, T. Yanagida, Molecular size dependence on the partial molar entropy change of liquid mixing, J. Mol. Liquid, 65/66, 381-384 (1995)

46. H. Higuchi, T. Yanagida, Y. E. Goldman, Compliance of thin filaments in skinned fibers of rabbit skeletal muscle, Biophys. J., 69, 1000-1010 (1995) [PUBMED]

45. T. Funatsu, Y. Harada, M. Tokunaga, K. Saito, T. Yanagida, Imaging of single fluorescent molecules and individual ATP turnovers by single myosin molecules in aqueous solution, Nature, 374, 555-559 (1995) [PUBMED]

44. T. Yanagida, A. Ishijima, Force and steps generated by single myosin molecules, Biophys. J., 68, 312-320 (1995) [PUBMED]


43. H. Kojima, A. Ishijima, T. Yanagida, Direct measurement of stiffness of sigle actin filaments with and without tropomyosin by in vitro nanomanipulation, Proc. Natl. Acad. Sci. USA, 91, 12962-12966 (1994) [PUBMED]

42. K. Saitoh, T. Aoki, T. Aoki, T. Yanagida, Movement of single myosin filaments and myosin step size on actin filament suspended in solution by a laser trap, Biophys. J, 66, 769-777 (1994)

41. A. Ishijima, Y. Harada, H. Kojima, T. Funatsu, H. Higuchi, T. Yanagida, Single-molecule analysis of the actomyosin motor using nano-manipulation, Biochem. Biophys. Res. Commun., 199, 1057-1063 (1994) [PUBMED]

40. S. Itakura, H. Yamakawa, Y. Toyoshima, A. Ishijima, H. Kojima, Y. Harada, T. Yanagida, T. Wakabayashi, K. Sutoh, Force-generating domain of myosin motor, Biochem. Biophys. Res. Commun., 196, 1504-1510 (1993) [PUBMED]

39. T. Yanagida, A. Ishijima, K. Saitoh, Y. Harada, Coupling between ATPase and force-generation attachment-detachment cycles of actomyosin in vitro, "Mechanism of Myofilament Sliding in Muscle Contraction" (H. Sugi eds.) Plenum Publishing Co. (New York) Adv. Exp. Med. Biol., 332, 339-349 (1993)

38. T. Yanagida, Y. Harada, A. Ishijima, Nano-manipulation of actomyosin molecular motors in vitro: A new working principle, Trends in Biochemical Sciences, 18, 319-324 (1993) [PUBMED]

37. E. Prochniewicz, E. Katayama, T. Yanagida, D. D. Thomas, Cooperativity in F-actin: Chemical modifications of actin monomers affect the functional interactions of myosin with unmodified monomers in the same actin filament, Biophys. J., 65, 113-123 (1993)

36. M. Johara, Y. Y. Toyoshima, A. Ishijima, H. Kojima, T. Yanagida, K. Sutoh, Charge-reversion mutagenesis of dictyostelium actin to map the surface recognized by myosin during ATP-driven sliding motion, Proc. Natl. Acad. Sci. USA, 90, 2127-2131 (1993)

35. E. M. Ostap, T. Yanagida, D. D. Thomas, Orientational distribution of spin-labeled actin oriented by flow, Biophys. J., 63, 966-975 (1992)

34. A. Ishijima, T. Doi, K. Sakurada, T. Yanagida, Sub-piconewton force fluctuations of actomyosin in vitro, Nature, 352, 301-306 (1991) [PUBMED]

33. T. Yanagida, Y. Harada, T. Kodama, Chemomechanical coupling in actomyosin system, an approach by in vitro movement assay and kinetic analysis of ATP hydrolysis by shortening myofibrils, Adv. Biophys., 27, 237-257 (1991) [PUBMED]

32. E. Prochniewicz, T. Yanagida, Mechanism of the active movement of actin: Is actin sliding directly or indirectly related to binding with myosin and activation of myosin ATPase?, Adv. Biophys., 27, 207-211 (1991) [PUBMED]

31. E. Prochniewicz, T. Yanagida, Inhibition of sliding movement of F-actin by crosslinking emphasizes the role of actin structure in the mechanism of motility, J. Mol. Biol., 216, 761-772 (1990) [PUBMED]

30. Y. Harada, K. Sakurada, T. Aoki, D. Thomas, T. Yanagida, Mechanochemical coupling in actomyosin energy transduction studied by in vitro movement assay, J. Mol. Biol., 216, 49-68 (1990) [PUBMED]

29. T. Yanagida, Loose coupling between chemical and mechanical reactions in actomyosin energy transduction, Adv. Biophys., 26, 75-95 (1990) [PUBMED]


28. Y. Harada, T. Yanagida, The elementary process in the acto-myosin energy transduction system, "Muscle Energetics" (R. J. Paul, G. Elzinga, K. Yamada eds.) Alan R. Liss, Inc., 27-36 (1989) [PUBMED]

27. A. Kishino, T. Yanagida, Force measurements by micromanipulation of a single actin filament by glass needles, Nature, 334, 74-76 (1988) [PUBMED]

26. T. Yanagida, Y. Harada, Minimum structural unt required for energy transduction in muscle, "Molecular Mechanism of Muscle Contraction" (H. Sugi, G. Pollack eds.), 277-287 (1988) [PUBMED]

25. Y. Harada, T. Yanagida, Direct observation of molecular motility by light microscopy, Cell Motility and the Cytoskeleton, 10, 71-76 (1988) [PUBMED]

24. T. Yanagida, F. Oosawa, Range of movement over which myosin cross-bridges can attach to actin filament during one ATP cycle, "Perspective of Biological Energy Transduction" Academic Press, 59-66 (1987)

23. Y. Harada, A. Noguchi, A. Kishino, T. Yanagida, Sliding movement of single actin filaments on one-headed myosin filaments, Nature, 326, 805-808 (1987) [PUBMED]

22. E. Prochniewicz-Nakayama, T. Yanagida, F. Oosawa, Movement of soluble fragments on actin bundle, "Actin: Structure and functions" (T. Yanagida eds.) Taniguchi Foundation, 235-242 (1986)

21. T. Yanagida, Myosin molecule can travel a distance of more than 60 nm on actin filaments during a single ATP cycle, "Actin: Structure and functions" (T. Yanagida eds.) Taniguchi Foundation, 228-234 (1986)

20. E. Prochniewicz-Nakayama, T. Yanagida, Sliding movement of HMM along F-actin bundle, J. Muscle Res. and Cell Motility, 7, 279 (1986) [DOI]

19. T. Yanagida, T. Arata, F. Oosawa, Sliding distance of actin filament induced by a myosin crossbridge during one ATP hydrolysis cycle, Nature, 316, 366-369 (1985) [PUBMED]

18. T. Yanagida, New sliding mechanism for muscle contraction and cell motility, "Cell Motility: Mechanism and Regulation" (H. Ishikawa, S. Hatano, H. Sato eds.) Univ. of Tokyo Press, 107-122 (1985)

17. T. Yanagida, Angle of active site of myosin heads in contracting muscle during sudden length changes, J. Muscle Res. and Cell Motility, 6, 43-52 (1985) [PUBMED]

16. T. Yanagida, Angles of fluorescently labelled myosin heads and actin monomers in contracting and rigor stained muscle fiber, "Contractile Mechanism in Muscle" (G. Pollack, H. Sugi eds.) Plenum Publishing Corporation, 397-411 (1984) [PUBMED]

15. T. Yanagida, M. Nakase, K. Nishiyama, F. Oosawa, Direct observation of motion of single F-actin filaments in the presence of myosin, Nature, 307, 58-60 (1984) [PUBMED]

14. H. Nagano, T. Yanagida, Predominant attached state of myosin cross-bridges during contraction and relaxation at low ionic strength, J. Mol. Biol., 177, 769-785 (1984) [PUBMED]

13. E. Prochniewicz-Nakayama, T. Yanagida, F. Oosawa, Studies on conformation of F-actin in muscle fibers in the relaxed state, rigor, and during contraction using fluorescent phalloidin, The Journal of Cell Biology, 97, 1663-1667 (1983) [PUBMED]

12. T. Yanagida, I. Kuranaga, A. Inoue, Interaction of myosin with thin filaments during contraction and relaxation: Effect of ionic strength, J. Biochem., 92, 407-412 (1982) [PUBMED]

11. E. Prochniewicz-Nakayama, T. Yanagida, The effect of crosslinking of thin filament with glutaraldehyde on the contractility of muscle fiber, J. Biochem. Tokyo., 92(4), 1269-1277 (1982) [PUBMED]

10. E. Prochniewicz, T. Yanagida, Comparison of intermonomer interactions within polymers of chicken gizzard and rabbit skeletal muscle actins, J. Biochem., 89, 1215-1221 (1981) [PUBMED]

9. T. Yanagida, Angles of nucleotides bound to cross-bridges in glycerinated muscle fiber at various concentrations ε-ATP, ε-ADP and ε-AMPPNP detected by polarized fluorescence, J. Mol. Biol., 146, 539-560 (1981) [PUBMED]

8. T. Yanagida, The angles of cross-bridges bound to nucleotide at various concentrations of Mg-(ε)-ATP, Muscle contraction: Its regulatory mechanisms (S. Ebashi, et al. eds.) Japan Sci. Soc. Press. Tokyo, 173-180 (1980)

7. T. Yanagida, F. Oosawa, Conformational changes of F-actin-ε-ADP in thin filaments in myosin-free muscle fibers induced by Ca2+, J. Mol. Biol., 140, 313-320 (1980) [PUBMED]

6. T. Yanagida, F. Oosawa, Polarized fluorescence from ε-ADP incorporated into F-actin in a myosin-free single fiber: Conformation of F-actin and changes induced in it by heavy meromyosin, J. Mol. Biol., 126, 507-524 (1978) [PUBMED]

5. T. Yanagida, Birefringence of glycerinated crab muscle fiber under various conditions, Biochim. Biophys. Acta, 420, 225-235 (1976) [PUBMED]

4. T. Yanagida, F. Oosawa, Effect of myosin on conformational changes of F-actin in thin filament in vivo induced by calcium ions, Eur. J. Biochem., 56, 547-556 (1975) [PUBMED]

3. T. Yanagida, M. Taniguchi, F. Oosawa, Conformational changes of F-actin in the thin filament of muscle induced in vivo and in vitro by calcium ions, J. Mol. Biol., 90, 509-522 (1974) [PUBMED]

2. T. Nishino, T. Yanagida, Y. Hamakawa, Impurity electroabsorption of GaAs, J. Appl. Phys., 11, 1221 (1972) [DOI]

1. T. Nishino, T. Yanagida, Y. Hamakawa, Exciton electroabsorption in germanium single crystal, J. Phys. Soc. Japan, 30, 579 (1971) [DOI]

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