Welcome to the Fukagawa Lab
We are studying on chromosome segregation.
We especially focus on the centromere and kinetochore.

News

2023.6.8
Paper has been published in Mol. Cell
2023.2.14
A collaborative study has been published in PNAS.: Evolutionary analysis of a complete chicken genome
2023.2.6
Paper has been published in EMBO J.: The cryo-EM structure of the CENP-A nucleosome in complex with ggKNL2
2022.2.14
Paper has been published in Nature Commun.: Recruitment of two Ndc80 complexes via the CENP-T pathway is sufficient for kinetochore functions
2021.1.19
Paper has been published in EMBO J.: Cryo‐EM structure of the CENP‐A nucleosome in complex with phosphorylated CENP‐C
2021.1.8
Paper has been published in Nature Commun.: Bridgin connects the outer kinetochore to centromeric chromatin
2020.11.17
Paper has been published in Cell Rep.: Essentiality of CENP-A depends on its binding mode to HJURP
2020.9.18
Prof. Fukagawa won the Kihara prize from GENETICS SOCIETY OF JAPAN
2019.12.2
Paper has been published in J. Cell Biol.: CDK1-mediated CENP-C phosphorylation modulates CENP-A binding and mitotic kinetochore localization
2018.11.12
We have just started Twitter @tatsuofukagawa1
2018.11.12
Paper has been published in Nature Cell Biol.: Multiple phosphorylations control recruitment of the KMN network onto kinetochores
2018.11.5
Paper has been published in J. Cell Biol.: 3D genomic architecture reveals that neocentromeres associate with heterochromatin regions
2017.7.24
Paper has been published in Dev. Cell: Association of M18BP1/KNL2 with CENP-A nucleosome is essential for centromere formation in non-mammalian vertebrates
2017.1.2
Paper has been published in J. Cell Biol.: Constitutive centromere-associated network controls centromere drift in vertebrate cells
2016.11.4
Paper has been published in Nature Commnications: Acetylation of histone H4 Lysine 5 and 12 is required for CENP-A deposition into centromeres
2015.9.9
Paper has been published in Mol. Biol. Cell: Dynamic changes in the CCAN organization through CENP-C during cell-cycle progression
2015.4.1
Our Lab has been moved to Osaka Univ from NIG
2014.6.23
Paper has been published in Dev. Cell: Centoromere modification for kinetochore assembly
2013.3.25
Paper has been published in Dev. Cell: Neocentromere formation using chromosome engineering.
2013.1.18
Paper has been published in EMBO. J.: Structural core for kinetochore formation.
2012.12.31
Featured in J. Cell Biol. “Comment”.
2012.12.31
Paper has been published in J. Cell Biol.: Creation of cell lines with the“stable” engineered kinetochores.
2012.6.21
Tatsuya Nishino was awarded a Young Scientist Award from Protein Science Society of Japan.
2012.2.3
Paper has been published in Cell: Histone-like structure in the kinetochore.
2012.2.3
Featured in Cell “Previews”
2011.4.29
Paper has been published in Cell: Creation of artificial kinetochores.
2011.4.6
Featured in J. Cell Biol. “In focus”
2011.4.4
Paper has been published in J. Cell Biol.: Kinetochore stretching by tension from spindle microtubules.
2011.2.18
Prof. Fukagawa was appointed Associate Editor on the Editorial Board of Chromosome Research.
2010.9.7
Paper has been published in Genome Res.: Sequencing of centromeric DNA in Chicken.
2009.7.27
Paper has been published in J. Cell Biol.: Identification and characterization of a novel kinetochore protein.
2008.12.12
Paper has been published Cell: Identification of the CENP-T-W complex.
2006.4.16
Paper has been published in Nature Cell Biol.: Identification of centromere proteins required for chromosome segregation.
2004.7.11
Paper has been published in Nature Cell Biol.: Chromosome segregation and RNAi in vertebrate cells.
2002.4.1
Paper has been published in Dev. Cell: Proteins required for innercentromere assembly in vertebrate cells.
2001.8.15
Paper has been published in EMBO J.: Centromere assembly in vertebrate cells.