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論文

2020

Detection of mitophagy in mammalian cells, mice, and yeast.  Calvelli Hannah, Krigman Judith, Onishi Mashun, Narendra Derek P, Sun Nuo, Okamoto Koji Methods in Cell Biology 155 557 - 579 2020年

マイトファジーの分子機構と生理的意義 (第5土曜特集 オートファジー : 分子機構・生物学的意義・疾患との関わり) -- (オートファジーの生物学的意義) 

大西 真駿, 岡本 浩二 医学のあゆみ 272(9) 801 - 810 2020年2月29日

2019

Repression of mitochondrial metabolism for cytosolic pyruvate-derived chemical production in Saccharomyces cerevisiae.  Morita Keisuke, Matsuda Fumio, Okamoto Koji, Ishii Jun, Kondo Akihiko, Shimizu Hiroshi Microbial Cell Factories 18(1) 177 - 177 2019年10月15日 

The Paf1 complex transcriptionally regulates the mitochondrial-anchored protein Atg32 leading to activation of mitophagy.
 
Zheng Liangde, Shu Wen-Jie, Li Yu-Min, Mari Muriel, Yan Chaojun, Wang Dehe, Yin Zhao-Hong, Jiang Wei, Zhou Yu, Okamoto Koji, Reggiori Fulvio, Klionsky Daniel J, Song Zhiyin, Du Hai-Ning Autophagy 1 - 14 2019年9月19日 

A Mammalian Mitophagy Receptor, Bcl2-L-13, Recruits the ULK1 Complex to Induce Mitophagy.  Murakawa Tomokazu, Okamoto Koji, Omiya Shigemiki, Taneike Manabu, Yamaguchi Osamu, Otsu Kinya Cell Reports 26(2) 338 - 345 2019年1月  

2018

  Mitochondrial stasis reveals p62-mediated ubiquitination in Parkin-independent mitophagy.
Yamada T, Murata D, Adachi Y, Itoh K, Kameoka S, Igarashi A, Dawson TM, Yanagawa T, Okamoto K, Iijima M, *Sesaki H.
Cell Metab., 28(4):588-57 (2018).

The TORC1 signaling pathway regulates respiration-induced mitophagy in yeast.
Liu Y, *Okamoto K.
Biochem. Biophys Res Commun. , doi:10.1016/j.bbrc.2018.04.114(2018).

The ER membrane insertase Get1/2 is required for efficient mitophagy in yeast.
Onishi M, Nagumo S, Iwashita S, *Okamoto K.
Biochem. Biophys Res Commun., doi: 10.1016/j.bbrc.2018.05.123 (2018).
 
The Nem1-Spo7 protein phosphatase complex is required for efficient mitophagy in yeast.
Xu X, *Okamoto K.
Biochem. Biophys Res Commun., 496(1):51-57 (2018).

<Reviews, Proceedings and Books>

  Phosphatidic acid and cardiolipin coordinate mitochondrial dynamics.
Kameoka S, Adachi Y, Okamoto K, Iijima M, *Sesaki H.
Trends Cell Biol., 28: 67-76. (2018).
 

2017

Investigation of Yeast Mitophagy with Fluorescence Microscopy and Western Blotting.
Nagumo S, *Okamoto K.
Methods Mol Biol., doi: 10.1007/7651_2017_11 (2017).

Assays for Mitophagy in Yeast.
Eiyama A, *Okamoto K.
Methods Mol Biol., 1567:337-347. (2017)
 
<Reviews, Proceedings and Books>

ミトコンドリア分別・除去システムの基本原理
*岡本浩二
The Frontiers in Life Sciencesシリーズ、「オートファジー」, 113-123., ISBN 978-4-525-13481-5 (2017).

2015

  Phospholipid methylation controls Atg32-mediated mitophagy and Atg8 recycling
Sakakibara K, Eiyama A, Suzuki SW, Sakoh-Nakatogawa M, Okumura N, Tani M, Hashimoto A, Nagumo S, Kondo-Okamoto N, Kondo-Kakuta C, Asai E, Kirisako H, Nakatogawa H, Kuge O, Takao T, Ohsumi Y, *Okamoto K.
EMBO J. 34: 2703-2719. (2015)

Protein N-terminal acetylation by the NatA complex is critical for selective mitochondrial degradation.
Eiyama A, *Okamoto K.
J. Biol. Chem. 290: 25034-25044.(2015)

<Reviews, Proceedings and Books>

Preface - The special issue on mitophagy.
*Okamoto K.
Biochim. Biophys. Acta 1853: 2755. (2015)

PINK1/Parkin-mediated mitophagy in mammalian cells.
Eiyama A, *Okamoto K.
Curr. Opin. Cell Biol. 33: 95-101.(2015)

2014

Enhancement of ethanol fermentation in Saccharomyces cerevisiae sake yeast by disrupting mitophagy function.
Shiroma S, Jayakody LN, Horie K, Okamoto K, *Kitagaki H.
Appl. Environ. Microbiol.80: 1002-1012.(2014)

<Reviews, Proceedings and Books>

Receptor-mediated mitophagy in yeast and mammalian systems.
Liu L, Sakakibara K, *Chen Q, *Okamoto K.
Cell Res. 24: 787-795.(2014)

Organellophagy: eliminating cellular building blocks via selective autophagy.
*Okamoto K.
J. Cell Biol. 205: 435-445.(2014)

Assays for autophagy II: Mitochondrial autophagy.
*Kanki T, Okamoto K.
Methods Mol. Biol. 1163: 165-173.(2014)

出芽酵母が語る選択的ミトコンドリア分解の基本原理. *岡本浩二. 医学のあゆみ・AYUMI「マイトファジー―基礎から疾患との関連まで」 250: 483-487.(2014)

2013

  Mitochondrial degradation during starvation is selective and temporally distinct from bulk autophagy in yeast.
Eiyama A, Kondo-Okamoto N, *Okamoto K.
FEBS Lett. 587: 1787-1792.(2013)

<Reviews, Proceedings and Books>

  No ATG is an island - the connection of autophagy with diverse pathways and functions.
*Komatsu M, Kuma A, Okamoto K.
EMBO Rep. 14: 219-221.(2013)

2012

  Autophagy-related protein 32 acts as autophagic degron and directly initiates mitophagy.
Kondo-Okamoto N, Noda NN, Suzuki SW, Nakatogawa H, Takahashi I, Matsunami M, Hashimoto A, Inagaki F, Ohsumi Y, *Okamoto K .
J. Biol. Chem.287: 10631-10638.(2012)

  <Reviews, Proceedings and Books>

Mitochondria and autophagy: critical interplay between the two hemostats.
Kondo-Okamoto N, *Okamoto K.
Biochim. Biophys. Acta 1820: 595-600.(2012)

  マイトファジーの分子機構.
*岡本浩二
DOJIN BIOSCIENCE SERIES 04,「オートファジー」. 133-149.(2012)

  ミトコンドリア品質管理研究の最前線.
*岡本浩二
細胞 THE CELL 44: 45-48.(2012)

2011

  Structure-function analysis of the yeast mitochondrial Rho GTPase, Gem1p: implications for mitochondrial inheritance.
Koshiba, T., Holman, H.A., Kubara, K., Yasukawa, K., Kawabata, S., Okamoto, K., MacFarlane, J., Shaw, J.M.
J. Biol. Chem. 286: 354-362. (2011)

<Reviews, Proceedings and Books>

Mitochondria breathe for autophagy.
Okamoto, K.
EMBO J. 30: 2095-2096.(2011)
 
Mitochondria autophagy in yeast.
Kanki, T., Klionsky, D.J., Okamoto, K.
Antioxid. Redox Signal.14:1989-2001.(2011)

2010

<Reviews, Proceedings and Books>

  酵母のマイトファジー〜観察からの始まり〜.顕微鏡
岡本徳子,岡本浩二,大隅良典
45: 83-86.(2010)

マイトファジー:ミトコンドリアを丸ごと分別・除去する仕組み.細胞工学・特集「その時ミトコンドリアは動いた」
岡本浩二*,岡本徳子
細胞工学・特集「その時ミトコンドリアは動いた」29: 423-428.(2010)

2009

  Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagy.
Okamoto, K.*, Kondo-Okamoto, N., and Ohsumi, Y.*
Dev. Cell,17: 87–97.(2009)

<Reviews, Proceedings and Books>

A landmark protein essential for mitophagy. Autophagy,
Okamoto, K.*, Kondo-Okamoto, N., and Ohsumi, Y.*
Autophagy, 5: 1203-1205.(2009)