大阪大学大学院 医学系研究科 病理学 幹細胞病理学/大阪大学大学院 生命機能研究科 時空生物学 病因解析学
Department of Pathology, Medical School and Graduate School of Frontier Biosciences, Osaka University

業績リスト

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2015年

  • Kimura T, Kaga Y, Sekita Y, Fujiwara K, Nakatani T, Odamoto M, Funaki S, Ikawa M, Abe K, Nakano T
    Pluripotent stem cells derived from mouse primordial germ cells by small molecule compounds
    Stem Cells, 33:45-55, 2015
  • Itou D, Shiromoto Y, Shin-ya Y, Ishii C, Nishimura T, Ogonuki N, Ogura A, KUramochi-Miyagawa, Nakano T
    Induction of DNA methylation by artificial piRNA production in male germ cells
    Current Biol, 25:901-906, 2015
  • Nakatani T, Yamagata K, Kimura T, Oda M, Nakashima H, Hori M, Sekita Y, Arakawa T, Nakamura T, Nakano T
    Stella preserves maternal chromosome integrity by inhibiting 5hmC-induced gH2AX accumulation
    EMBO Rep, 16:582-589, 2015
  • Kimura Y, Oda M, Nakatani T, Sekita Y, Monnfort A, Wutz A, Mochizuki H, Nakano T
    CRISPR/Cas9-mediated reporter knock-in in mouse haploid embryonic stem cells
    Sci Rep, 5:10710, 2015
  • Arakawa T, Nakatani T, Oda M, Kimura Y, Sekita Y, Kimura T, Nakamura T, Nakano T.
    Stella controls chromocenter formation through regulation of Daxx expression in 2-cell embryos
    Biochem Biophys Res Commun, 466:60-5, 2015
  • Kimura Y, Oda M, Nakatani T, Sekita Y, Monnfort A, Wutz A, Mochizuki H, Nakano T
    CRISPR/Cas9-mediated reporter knock-in in mouse haploid embryonic stem cells
    Sci Rep, 5:10710, 2015
  • Nagamori I, Kobayashi H, Shiromoto Y, Nishimura T, Kuramochi-Miyagawa S, Nakano T.
    Comprehensive DNA methylation analysis of retrotransposons in male germ cells
    Cell Rep, 12:1541-7, 2015
  • Matsuzaki H, Okamura E, Takahashi T, Ushiki A, Nakamura T, Nakano T, Hata K, Fukamizu A, Tanimoto K..
    De novo DNA methylation through the 5'-segment of the H19 ICR maintains its imprint during early embryogenesis
    Development, 142:3833-44, 2015

2014年

  • Kimura T, Kaga Y, Ohta H, Odamoto M, Sekita Y, Li K, Yamano N, Fujiwara K, Isotani A, Sasaki N, Toyoda M, Hayashi K, Okabe M, Shinohara T, Saitou M, Nakano T
    Induction of primordial germ cell-like cells from mouse embryonic stem cells by ERK signal inhibition
    Stem Cells, 32:2668-78, 2014
  • Matsui Y, Takehara A,Tokitake Y, Ikeda M, Obara Y, Morita-Fujimura Y, Kimura T, Nakano T
    The majority of early PGCs acquire pluripotency by AKT activation
    Development, 141: 1-11, 2014
  • Funaki S, Nakamura T, Nakatani T, Umehara H, Nakashima H, Nakano T
    Inhibition of maintenance DNA methylation by Stella
    BBRC, 453: 455-60, 2014
  • Kuramochi-Miyagawa S, Kita-Kojima K, Shiromoto Y, Ito D, Koshima H, Nakano T
    DNA methylation in mouse testes
    Methods Mol Biol, 1093:97-109, 2014
  • Ichiyanagi T, Ichiyanagi K, Ogawa A, Kuramochi-Miyagawa S, Nakano T, Chuma S, Sasaki H, Udono H
    HSP90a plays an important role in piRNA biogenesis and retrotransposon repression in mouse
    Nucl Acid Res, 42: 11903-11, 2014

2013年

  • Nakashima H, Kimura T, Kaga Y, Nakatani T, Seki Y, Nakamura T, Nakano T
    Effects of Dppa3 on DNA methylation dynamics during primordial germ cell development
    Biol Rep, 88:109-117, (Journal Cover), 2013
  • Yamamoto Y, Watanabe T, Hoki Y, Shirane K, Li Y, Ichiiyanagi K, Kuramochi-Miyagawa S, Toyoda A, Fujiyama A, Oginuma M, Suzuki H, Sado T, Nakano T, Sasaki H
    Targeted gene silencing in mouse germ cells by insertion of a homologous DNA into a piRNA generating locus
    Genome Res, 23:292-299, 2013
  • Shiromoto Y, Kuramochi-Miyagawa S, Daiba A, Chuma S, Katanaya A, Nishimura K, Ohtaka M, Nakanishi M, Nakamura T, Yoshinaga K, Asada N, Nakamura S, Yasunaga T, Kojima-Kita K, Itou D, Kimura T, Nakano T
    GPAT2, a Mitochondrial Outer Membrane Protein, in piRNA Biogenesis in Germline Stem Cells
    RNA, 23:292-299, 2013
  • Chuma S, Nakano T
    piRNA and spermatogenesis in mice
    Philos Trans R Soc Lond B Biol Sci, 368:20110338, 2013

2012年

  • Nakamura T, Liu YU, Nakashima H, Umehara H, Inoue K, Matoba S, Tachibana M, Ogura A, Shinkai Y, Nakano T
    PGC7 binds histone H3K9me2 to protect against conversion of 5MeC to 5HmC in early embryos
    Nature,486: 415-9, 2012
  • Liu YJ, Nakamura T, Nakano T
    Essential role of DPPA3 for chromatin condensation in mouse oocytogenesis
    Biol Rep,86:1-8, 2012
  • Ohishi K, Nakano T
    A forward genetic screen to study mammalian RNA interference - essential role of RNase IIIa domain of Dicer1 in 3' strand cleavage of dsRNA in vivo
    FEBS J, 279:832-43, 2012
  • Nishibu T, Hayashida Y, Tani S, Kurono S, Kojima-Kita K, Ukekawa R, Kurokawa T, Kuramochi-Miyagawa S, Nakano T, Inoue K, Honda S
    Identification for MIWI-associated poly(A) RNAs by immunoprecipitation with an anti-MIWI monoclonal antibody
    Bioscience Trends, 6:248-261, 2012
  • Nishio M, Hamada K, Kawahara K, Sasaki M, Noguchi F, Chiba S, Mizuno K, Suzuki SO, Dong Y, Tokuda M, Morikawa T, Hikasa H, Eggenschwiler J, Yabuta N, Nojima H, Nakagawa K, Hata Y, Nishina H, Mimori K, Mori M, Sasaki T, Mak TW, Nakano T, Itami S, Suzuki A
    Cancer susceptibility and embryonic lethality in Mob1a/1b double-mutant mice
    J Clin Inv, 122:4505-4518, 2012

2011年

  • Kitajima K, Minehata K, Sakimura K, Nakano T, Hara T
    In vitro generation of HSC-like cells from murine ESCs/iPSCs by enforced expression of LIM-homeobox transcription factor Lhx2
    Blood, 117:3748-3758, 2011
  • Sasaki M, Kawahara K, Nishio M, Mimori K, Kogo R, Hamada K, Itoh B, Wang J, Komatsu Y, Yang YR, Hikasa H, Horie Y, Yamashita T, Kamijo T, Zhang Y, Zhu Y, Prives C, Nakano T, Mak TW, Sasaki T, Maehama T, Mori M, Suzuki A
    Regulation of the MDM2-P53 pathway and tumor growth by PICT1 via nucleolar RPL11
    Nat Med, 17: 944-951, 2011
  • Tanaka T, Hosokawa M, Vagin VV, Reuter M, Hayashi E, Mochizuki AL, Kitamura K, Yamanaka H, Kondoh G, Okawa K, Kuramochi-Miyagawa S, Nakano T, Sachidanandam R, Hannon GJ, Pillai RS, Nakatsuji N, Chuma S.
    Tudor domain containing 7 (Tdrd7) is essential for dynamic ribonucleoprotein (RNP) remodeling of chromatoid bodies during spermatogenesis.
    Proc Natl Acad Sci USA, 108:10579-10584, 2011
  • Tanaka SS, Yamaguchi YL, Steiner KA, Nakano T, Nishinakamura R, Kwan KM, Behringer RR, Tam PP
    Loss of Lhx1 activity impacts on the localization of primordial germ cells in the mouse
    Dev Dyn, 239:2851-9, 2011
  • Wossidlo M, Nakamura T, Lepikhov K, Marques J, Zakhartchenko V, Boiani M, Arand J, Nakano T, Reik W, Walter J
    5-hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming
    Nature Commun, 2:241, 2011
  • Watanabe T, Chuma S, Yamamoto Y, Kuramochi-Miyagawa S, Totoki Y, Toyoda A, Hoki Y, Fujiyama A, Shibata T, Sado T, Noce T, Nakano T, Nakatsuji N, Lin H, Sasaki H
    MitoPLD Is a Mitochondrial Protein Essential for Nuage Formation and piRNA Biogenesis in the Mouse Germline
    Dev Cell, 20:364-375, 2011
  • Ikegami D, Akiyama H, Suzuki A, Nakamura T, Nakano T, Yoshikawa H, Tsumaki N
    Sox9 sustains chondrocyte survival and hypertrophy in part through Pik3ca-Akt pathways
    Development, 138:1507-1519, 2011
  • Kimura T, Nakano T
    Induction of pluripotency in primordial germ cells
    Histol Histopathol, 26:643-650, 2011
  • Watanabe T, Tomizawa S, Mitsuya K, Totoki Y, Yamamoto Y, Kuramochi-Miyagawa S, Iida N, Hoki Y, Murphy PJ, Toyoda A, Gotoh K, Hiura H, Arima T, Fujiyama A, Sado T, Shibata T, Nakano T, Lin H, Ichiyanagi K, Soloway PD, Sasaki H.
    Role for piRNAs and a novel non-coding RNA in de novo DNA methylation of the imprinted mouse Rasgrf1 locus
    Science, 332:848-852, 2011       
  • Sasaki M, Kawahara K, Nishio M, Mimori K, Kogo R, Hamada K, Itoh B, Wang J, Komatsu Y, Yang YR, Hikasa H, Horie Y, Yamashita T, Kamijo T, Zhang Y, Zhu Y, Prives C, Nakano T, Mak TW, Sasaki T, Maehama T, Mori M, Suzuki A.
    Regulation of the MDM2-P53 pathway and tumor growth by PICT1 via nucleolar RPL11
    Nat Med332:848-85251, 2011
  • Tanaka T, Hosokawa M, Vagin VV, Reuter M, Hayashi E, Mochizuki AL, Kitamura K, Yamanaka H, Kondoh G, Okawa K, Kuramochi-Miyagawa S, Nakano T, Sachidanandam R, Hannon GJ, Pillai RS, Nakatsuji N, Chuma S.
    Tudor domain containing 7 (Tdrd7) is essential for dynamic ribonucleoprotein (RNP) remodeling of chromatoid bodies during spermatogenesis
    Proc Natl Acad Sci USA, 108:10579-10584, 2011
  • Ichiyanagi K, Li Y, Watanabe T, Ichiyanagi T, Fukuda K, Kitayama J, Yamamoto Y, Kuramochi-Miyagawa S, Nakano T, Yabuta Y, Seki Y, Saitou M, Sasaki H.
    Locus- and domain-dependent control of DNA methylation at mouse B1 retrotransposons during male germ cell development
    Genome Res, 21:2058-66, 2011
  • Matoba S, Inoue K, Kohda T, Sugimoto M, Mizutani E, Ogonuki N, Nakamura T, Abe K, Nakano T, Ishino F, Ogura A.
    RNAi-mediated knockdown of Xist can rescue the impaired postimplantation development of cloned mouse embryos
    Proc Natl Acad Sci USA, 108:20621-6, 2011

2010年

  • Kuramochi-Miyagawa S, Watanabe T, Gotoh K, Takamatasu K, Chuma S, Kojima-Kita K, Shiromoto Y, Asada N, Toyoda A, Fujiyama A, Totoki Y, Shibata T, Kimura T, Nakatsuji N, Noce T, Sasaki H, Nakano T.
    MVH in piRNA processing and gene silencing of retrotransposons
    Genes Dev, 24:887-892, 2010
  • Yamano N, Kimura T, Watanabe-Kushima S, Shinohara T, Nakano T.
    Metastable primordial germ cell-like state induced from mouse embryonic stem cells by Akt activation
    Biochem Biophys Res Commun, 392:311-316, 2010
  • Huang CL, Cheng JC, Kitajima K, Nakano T, Yeh CF, Chong KY, Tseng CP
    Disabled-2 is required for mesoderm differentiation of murine embryonic stem cells
    J Cell Physiol, 225:92-105, 2010

2009年

  • Sakai E, Kitajima K, Sato A, Nakano T.
    Increase of hematopoietic progenitor and suppression of endothelial gene expression by Runx1 expression during in vitro ES differentiation.
    Exp Hematol. 37:334-345, 2009.
  • Unhavaithaya Y, Hao Y, Beyret E, Yin H, Kuramochi-Miyagawa S, Nakano T, Lin H.
    MILI, a piRNA binding protein, is required for germline stem cell self-renewal and appears to positively regulate translation.
    J Biol Chem, 284:6507-6519, 2009
  • Kojima K, Kuramochi-Miyagawa S, Chuma S, Tanaka T, Nakatsuji N, Kimura T, Nakano T.
    Associations between PIWI proteins and TDRD1/MTR-1 are critical for integrated subcellular localization in murine male germ cells.
    Genes Cells, 14:1155-1165, 2009
  • Yoshimura T, Toyoda S, Kuramochi-Miyagawa S, Miyazaki T, Miyazaki S, Tashiro F, Yamato E, Nakano T, Miyazaki J.
    Gtsf1/Cue110, a gene encoding a protein with two copies of a CHHC Zn-finger motif, is involved in spermatogenesis and retrotransposon suppression in murine testes.
    Dev Biol, 335:216-217, 2009
  • Shoji M, Tanaka T, Hosokawa M, Reuter M, Stark A, Kato Y, Kondoh G, Okawa K, Chujo, Suzuki T, Hata K, Martin S, Noce T, Kuramochi-Miyagawa S, Nakano T, Sasaki H, Pillai RS, Nakatsuji N, Chuma S.
    The TDRD9-MIWI2 complex is essential for piRNA-mediated retrotransposon silencing in the mouse male germline
    Dev Cell, 17:775-787, 2009

2008年

  • Kimura T, Tomooka M, Yamano N, Murayama K, Matoba S, Umehara H, Kanai Y, Nakano T
    Akt signaling promotes derivation of embryonic germ cells from primordial germ cells
    Development, 135:869-79, 2008
  • Sugiyama D, Tanaka M, Kitajima K, Zheng J, Yen H, Murotani T, Yamatodani A, Nakano T
    Differential context-dependent effects of FOG-1 on mast cell development and differentiation.
    Blood, 111:1924-32, 2008
  • Tamaru S, Kitajima K, Nakano T, Eto K, Yazaki A, Kobayashi T, Matsumoto T, Wada H, Katayama N, Nishikawa M.
    Calyculin A retraction of mature megakaryocytes proplatelets from embryonic stem cells.
    Biochem Biophys Res Commun, 366:763-8, 2008
  • Kuramochi-Miyagawa S, Watanabe T, Gotoh K, Totoki Y, Toyoda A, Ikawa M, Asada N, Kojima K, Yamaguchi Y, Ijiri T, Hata K, Li E, Matsuda Y, Kimura T, Okabe M, Sakaki Y, Sasaki H, Nakano T
    DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes.
    Genes Dev, 22:918-30, 2008
  • Watanabe T, Totoki Y, Toyoda A, Kaneda M, Kuramochi-Miyagawa S, Obata Y, Chiba H, Kohara Y, Kono T, Nakano T, Surani MA, Sakaki Y, Sasaki H.
    Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes.
    Nature, 453:539-43, 2008
  • Kita K, Kimura T, Nakamura N, Yoshikawa H, Nakano T.
    PI3K/Akt signaling as a key regulatory pathway for chondrocyte terminal differentiation.
    Genes Cells, 13:839-850, 2008
  • Nakamura T, Inoue K, Ogawa S, Umehara H, Ogonuki N, Miki H, Kimura T, Ogura A, Nakano T.
    Effects of Akt signaling on nuclear reprogramming.
    Genes Cells, 13:1269-1277, 2008

2007年

  • Nakamura T, Arai Y, Umehara H, Masuhara M, Kimura T, Taniguchi H, Sekimoto T, Ikawa M, Yoneda Y, Okabe M, Tanaka S, Shiota K, Nakano T
    PGC7/Stella protects against DNA demethylation in early embryogenesis
    Nature Cell Biol, 9: 64-71, 2007
  • Chen L, Shen R, Ye Y, Pu XA, Liu X, Duan W, Wen J, Zimmerer J, Wang Y, Liu Y, Lasky LC, Heerema NA, Perrotti D, Ozato K, Kuramochi-Miyagawa S, Nakano T, Yates AJ, Carson Iii WE, Lin H, Barsky SH, Gao JX
    Precancerous stem cells have the potential for both benign and malignant differentiation
    PLoS ONE. Mar 14;2:e293, 2007
  • Murayama K, Kimura T, Tarutani M, Tomooka M, Hayashi R, Okabe M, Nishida K, Itami S, Katayama I, Nakano T
    Akt activation induces epidermal hyperplasia and proliferation of epidermal progenitors.
    Oncogene, 26:4882-8, 2007
  • Lee J, Kanatsu-Shinohara M, Inoue E, Ogonuki N, Miki H, Toyokuni S, Kimura T, Nakano T, Ogura A, Shinohara T
    Akt mediates self-renewal division of mouse spermatogonial stem cells.
    Development, 134: 1853-1859, 2007
  • Kishimoto H, Ohteki T, Yajima N, Kawahara K, Natsui M, Kawarasaki S, Hamada K, Horie Y, Kubo Y, Arase S, Taniguchi M, Vanhaesebroeck B, Mak TW, Nakano T, Koyasu S, Sasaki T, Suzuki
    Pten/PI3K pathway governs the homeostasis of Valpha14iNKT cells.
    Blood, 109: 3316-24, 2007
  • Umehara H, Kimura T, Ohtsuka S, Nakamura T, Kitajima K, Ikawa M, Okabe M, Niwa H, Nakano T
    Efficient derivation of embryonic stem cells by inhibition of glycogen synthase kinase-3.
    Stem Cells, 25:2705-11, 2007

2006年

  • Zheng J, Kitajima K, Sakai E, Kimura T, Minegishi N, Yamamoto M, Nakano T
    Differential Effects of GATA-1 on Proliferation and Differentiation of Erythroid Lineage Cells
    Blood, 107:520-527, 2006
  • Watanabe S, Umehara H, Murayama K, Okabe M, Kimura T, Nakano T
    Activation of Akt Signaling is Sufficient to Maintain Pluripotency in Mouse and Primate Embryonic Stem Cells
    Oncogene, 25:2697-707, 2006
  • Kitajima K, Tanaka M, Yen H, Sato A, Sugiyama D, Umehara H, Sakai E, Nakano T
    Redirecting Differentiation of Hematopoietic Progenitors by a Transcription Factor GATA-2
    Blood, 2006, 107:1857-63, 2006
  • Kitajima K, Zheng J, Yen H, Sugiyama D, Nakano T
    Multipotential differentiation ability of GATA-1 null erythroid committed cells
    Genes & Development, 20:654-9, 2006
  • Aravin A, Gaidatzis D, Pfeffer S, Lagos-Quintana M, Landgraf P, Iovino N, Morris P, Brownstein MJ, Kuramochi-Miyagawa S, , Nakano T, Chien M, Russo JJ, Ju J, Sheridan R, Sander C, Zavolan M, Tuschl T
    A novel class of small RNAs bind to MILI protein in mouse testes
    Nature, 442:203-7, 2006
  • Lau NC, Seto AG, Kim J, Kuramochi-Miyagawa S, Nakano T, Bartel DP, Kingston RE
    Characterization of the piRNA complex from rat testes
    Science, 313:363-7, 2006
  • Tsuruta H, Kishimoto H, Sasaki T, Natsui M, Shibata Y, Tsuchiya N, Horie Y, Hamada K, Yajima N, Enomoto K, Gordon JI, Mak TK, Nakano T, Habuchi T, Suzuki A
    Hyperplasia and carcinomas in Pten-deficient mice and reduced PTEN protein in human bladder cancer patients
    Can Res, 66: 8389-8396, 2006
  • Hamazaki T, Kehoe SM, Nakano T, Terada N
    The Grb2/mek pathway represses Nanog in murine embryonic stem cells.
    Mol Cell Biol, 26: 7539-7549, 2006
  • Kimura T, Nakamura T, Maruyama K, Umehara H, Taketo MM, Nakano T
    Stabilization of β-catenin leads to impaired primordial germ cell development by aberrant cell cycle progression
    Developmental Biology, 300: 545-553, 2006
  • Liebe B, Petukhova G, Barchi M, Bellani M, Braselmann H, Nakano T, Pandita TK, Jasin M, Fornace A, Meistrich ML, Baarends WM, Schimenti J, de Lange T, Keeney S, Camerini-Otero RD, Scherthan H. Mutations that affect meiosis in male mice influence the dynamics of the mid-preleptotene and bouquet stages.
    Exp Cell Res, 312: 3768-3781, 2006

〜2005年

  • Kuramochi-Miyagawa K, Kimura T, Ijiri T, Asada N, Fujita Y, Ikawa M, Isobe T, Iwai N, Okabe M, Deng W, Lin H, Matsuda Y, Nakano T
    mili, a mammalian member of piwi family gene, is essential for spermatogenesis
    Development, 131:839-849, 2004
  • Horie Y, Suzuki A, Kataoka E, Sasaki T, Hamada K, Sasaki J, Mizuno K, Hasegawa G, Kishimoto H, Iizuka M, Naito M, Enomoto K, Watanabe S, Mak TW, Nakano T
    Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas
    J Clin Invest, 113: 1774-1783, 2004
  • Suzuki A, Kaisho T, Ohishi M, Tsukio-Yamaguchi M, Tsubata T, Koni PA, Sasaki T, Mak TW, Nakano T.
    Critical roles of Pten in B cell homeostasis and immunoglobulin class switch recombination
    J Exp Med, 197: 657-67, 2003
  • Kimura T, Suzuki A, Fujita Y, Yomogida K, Lomeli H, Asada N, Ikeuchi M, Nagy A, Mak TW, Nakano T.
    Conditional loss of PTEN leads to testicular teratoma and enhances embryonic germ cell production
    Development, 130: 1691-1700, 2003
  • Nakano T
    Hematopoietic stem cells: generation and manipulation
    Trends Immunol, 24: 589-594, 2003
  • Kitajima K, Masuhara M, Era T, Enver T, Nakano T.
    GATA-2 and GATA-2/ER display opposing activities in the development and differentiation of blood progenitors.
    EMBO J, 21:3060-69, 2002
  • Iwai N, Kitajima K, Sakai K, Kimura T, Nakano T.
    Alteration of cell adhesion and cell cycle properties of ES cells by an inducible dominant interfering Myb mutant.
    Oncogene, 20:1425-34, 2001
  • Suzuki A, Tsukio-Yamaguchi M, Ohteki T, Sasaki T, Kaisho T, Kimura Y, Yoshida R, Wakeham A, Higuchi T, Fukumoto M, Tsubata T, Ohashi P, Koyasu S, Penninger J M, Nakano T. (corresponding author), Mak T W.
    T-cell specific loss of PTEN leads to defects in central and peripheral tolerance.
    Immunity, 14:523-34, 2001
  • Era T, Takagi Y, Takahashi T, Bories J C, Nakano T.
    Characterization of hematopoietic lineage specific gene expression by ES cell in vitro differentiation induction system.
    Blood, 95: 870-878, 2000
  • Takahashi T, Suwabe N, Dai P, Yamamoto M, Ishii S, Nakano T.
    Inhibitory interaction of c-Myb and GATA-1 via transcriptional co-activator CBP.
    Oncogene, 19:134-40, 2000
  • Motoyama N, Kimura T, Takahashi T, Watanabe T, Nakano T.
    bcl-x prevents apoptotic cell death of both primitive and definitive erythrocytes at the end of maturation.
    J Exp Med, 189: 1691-1698, 1999
  • Era T, Takahashi T, Sakai K, Kawamura K, Nakano T.
    Thrombopoietin enhances proliferation and differentiation of murine yolk sac erythroid progenitors.
    Blood, 89:1207-1213, 1997
  • Nakano T, Kodama H, Honjo T.
    In vitro development of primitive and definitive erythrocytes from different precursors.
    Science, 272:722-724, 1996
  • Nakano T, Kodama H, Honjo T.
    Generation of lymphohematopoietic cells from embryonic stem cells in culture.
    Science, 265:1098-1101, 1994
  • Tashiro K, Tada H, Shirozu M, Heilker R, Nakano T, Honjo T.
    Signal sequence trap: A cloning strategy for secreted proteins and type I transmembrane proteins.
    Science, 261:600-603, 1993
  • Introna M, Golay J, Frampton J, Nakano T, Ness S A, Graf T.
    Mutations in v-myb alter the differentiation of myelomonocytic cells transformed by the oncogene.
    Cell, 63:1287-1297, 1990
  • Nakano T, Waki N, Asai H, Kitamura Y.
    Lymphoid differentiation of the hematopoietic stem cell that reconstitutes total erythropoiesis of a genetically anemic W/Wv mouse.
    Blood, 73:1175-1179, 1989
  • Nakano T, Waki N, Asai H, Kitamura Y.
    Long term monoclonal reconstitution of erythropoiesis in genetically anemic W/Wv mice by injection of 5-fluorouracil treated bone marrow cells of Pgk-1b/Pgk-1a mice.
    Blood, 70:1758-1763, 1987
  • Nakano T, Sonoda T, Hayashi C, Yamatodani A, Kanayama Y, Yamamura T, Asai H, Yonezawa T, Kitamura Y, Galli S J.
    Fate of bone marrow derived cultured mast cells after intracutaneous, intraperitoneal and intravenous transfer into mast cell-deficient W/Wv mice; evidence that cultured mast cells can give rise to both connective tissue type and mucosal mast cells.
    J Exp Med, 162:1025-1043, 1985
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