Report of The ASCB 2013 Annual Meeting And The Other Destinations
2013.12.8 - 19
(Laboratory of Biological Science, Graduate School of Frontier Bioscience, Osaka University)
It was a long and grateful journey in America. Presenting my research and learning the latest information in the ASCB 2013 annual meeting and visiting other places was truly impressive.
On this trip, I presented my study, titled "Dose-dependent role of claudin-1 in epidermal differentiation and inflammation over time". In General, knock out or knock down strategies are used to understand gene functions, like a switch that turns "on" and "off" gene expressions. However, in the case of diseases, it is easy to consider the reduction of gene expression by any other factors but not a direct genetic problem. So, I focused on claudin1, which has a key role in epidermal barrier systems.
In our previous study, claudin-1 knockout (KO) mice died within one day after birth due to dehydration. It remains unknown how claudin-1 contributes to epidermal homeostasis with aging. To observe these, I established in vivo analysis system 6 pattern mice of expression levels of claudin1. The mice with low claudin-1 expression showed abnormal skin differentiation and inflammation in the infant stage, but significant improvement in the adult stage. I discussed the results with detailed reference to the expression levels of claudin-1 regulating various phenotypes in this trip.
The journey started from New York City, I visited Rakuten Institute of technology (RIT-NY). We discussed our case studies with each other. It was attractive for me to think about IT technology because I usually think "how to use IT" but not "IT research". There is a natural language processing facility in RIT-NY. Rakuten Inc. has many huge societies of Internet shopping websites around the world, especially in Japan. Researchers in RIT-NY showed me their research on collecting precious information from Raketen's database. They have also demonstrated in their studies how the system can give smart suggestions like a salesperson to customers. It was an interesting experience for me to think my future career in the IT industry. I appreciate for Dr. Sekine and Dr. Hagiwara for giving me a chance to visit the institute.
Then, we met Dr. Caplan in Yale University, New Heaven. I listened to the presentation by Yale researchers. Fortunately, I got a chance to introduce my latest research to Dr. Caplan. And he gave me great ideas for my work. It was very impressive.
Finally, I attended the annual meeting of the American Society of Cell Biology (ASCB) that was held in New Orleans. This was the main event for me. I went to present my research using poster presentation to whoever was interested. I was happy to discuss my study because there are not many researchers in our field in Japan. Of course, I was able to talk with other researchers who majored in other fields related to my research as well. Unfortunately, the flight schedule didn't cover all day of the meeting. But I attended many symposiums despite the tight schedule as long as I can.
Additionally, I would like to write down two important things expected on my presentation. First, technological development is faster than I thought. It means I should work harder. Second, when I walked around the poster presentation of undergraduate students, I felt their passion for science! Recently I got blinded by greed such as degree, paper, impact, etc.... I thought I should reset myself before graduate of my Ph.D course.
Through this journey, I had many opportunities to introduce my research and to learn out-side studies. If I didn't join this trip, I wouldn't be able to experience these. During this trip, I was able to know what other researchers think of my research. It was the greatest achievement for me. Now I am writing a journal, which include the advices and experience I received from various experts and researchers. Lastly, I appreciate the support given by Takuetsu program of our graduate school, which gave me a chance to join this trip.
2014.2.14 - 23
2014.2.14 - 23
2014.1.12 - 18
2013.12.8 - 19
2013.11.8 - 16
2013.11.8 - 15
2013.11.8 - 16
2013.9.9 - 15
2013.10.13 - 18
2013.8.24 - 9.1