Global COE seminars
Dr. Kyonsoo Hong| Affiliation | Director, Electron Imaging Center for NanoMachines (EICN) |
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| Date | May 16, 2011 |
| Place | 2nd floor Seminar room, Annex Bldg., Suita Campus |
| Host Lab. | 特別研究推進講座／ソフトバイオシステム研究室（柳田研） |
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GCOE Program Invited Speaker's Seminar
"Structural diversity among members of the Reoviridae,
viruses infecting plants, insects, and human"
Dr. Z. Hong Zhou
Director, Electron Imaging Center for NanoMachines (EICN)
Professor, Department of Microbiology, Immunology and Molecular Genetics, University of California
Member, ACCESS Program, California NanoSystems Institute, UCLA
Date: June 9, 2011
Time: 16:00-17:00
Place: Seminar room (3rd floor) in Nanobiology building,
Suita Campus
Reoviridae is a large family of non-enveloped, dsRNA viruses which infects plants, insects, animals, including humans. Despite sharing a inner core, these viruses have striking variations in their architectures. While most viruses in this family have triple shells, some have double and single shells and the reason underlying this striking variation has been a mystery.
I will illustrate how we use single particle cryo electron microscopy(cryoEM) to determine their structures, up to atomic details. These structures reveal divergent mechanisms employed by these viruses to infect different hosts, while maintaining a conserved core structure to perform their conserved function of RNA transcription and replication.
