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Biomolecular Networks Laboratories Biomolecular Dynamics Group (Prof. Yoneda)
Nanobiology Laboratories
Soft Biosystem Group
Protonic NanoMachine Group
Sensory Transduction Group

Biomolecular Networks Laboratories
Research Group of Lipid Biosignals
Biomolecular Dynamics Group 
Developmental Biology Group
Chromosome Replication Group

Integrated Biology Laboratories
Laboratory of Genetics
Pathology Division
KOKORO-Biology Group
Cellular Biology Group

Organismal Biosystems Laboratories
Laboratory of Developmental Immunology
Developmental Genetics Group
Human Cell Biology Group
Medicine and Pathophysiology Group

Neuroscience Laboratories
Visual Neuroscience Group
Developmental and Functional Neuroscience Group
Cognitive Neuroscience Group
Cellular and Molecular Neurobiology Group
Synaptic Plasticity Group

Biophysical Dynamics Laboratories
Physiological Laboratory
Nonequilibrium Physics Group
Functional Proteomics Group
Nano-Biophotonics Group

Biomedical Engineering Laboratories
Systems Neuroscience Group
Department of Molecular Genetics
Laboratory of Intercellular Communications
Laboratory of Stem Cell Research
Laboratory of Protein Informatics
Laboratory of Biocatalysis Science

Collaborative institutes
Laboratory of Immune Regulation Chugai Pharmaceutical CO.,LTD.
Optical Nano Device Group
OMRON Corporation

  Publications

Yoneda, Y. Protein transport.
Nature Encyclopedia of the Human Genome, Nature Publishing Group, Vol. 4, pp. 873-878 (2003)

96) Miyamoto, Y., Saiwaki, T., Yamashita, J., Yasuda, Y., Kotera, I., Shibata, S., Shigeta, M., Hiraoka, Y., Haraguchi, T., and Yoneda, Y.
Cellular stresses induce the nuclear accumulation of importin a and cause a conventional nuclear import block.
J. Cell Biol., in press (2004)

95) Sekimoto, T., Fukumoto, M., and Yoneda, Y.
14-3-3 suppresses the nuclear localization of threonine 157-phosphorylated p27Kip1.
EMBO J., in press (2004)

94) Yasuhara, N., Takeda, E., Inoue, H., Kotera, I., and Yoneda, Y.
Importin a/b-mediated nuclear protein import is regulated in a cell cycle-dependent manner.
Exp. Cell Res., in press (2004)

93) Furuta, M., Kose, S., Koike, M., Shimi, T., Hiraoka, Y., Yoneda, Y., Haraguchi, T., and Imamoto, N.
Heat-shock induced nuclear retention and recycling inhibition of importin a.
Genes Cells, in press (2004)

92) Sakaguchi,N., Miyamoto,Y., Yoneda,Y., Ogino,K. and Tachibana,T.
Generation of a rat monoclonal antibody specific for importin alpha3/Qip1.
Hybridoma and Hybridomics, 22: 397-400 (2003)

91) Lee, S. J., Sekimoto, T., Yamashita, E., Nagoshi, E., Nakagawa, A., Imamoto, N., Yoshimura, M., Sakai, H., Chong, K. T., Tsukihara, T. and Yoneda, Y.
The structure of importin b bound to SREBP-2: Insights into nuclear import of a transcription factor.
Science, 302: 1571-1575 (2003)

90) Konishi, A., Shimizu, S., Hirota, J., Takao, T., Fan, Y., Matsuoka, Y., Zhang, L., Yoneda, Y., Fujii, Y., Skoultchi, A. I., and Tsujimoto, Y.
Involvement of histone H1.2 in apoptosis induced by DNA double-strand breaks
Cell, 114: 673-688 (2003)

89) Lee, S. J., Sekimoto, T., Yamashita, E., Nagoshi, E., Nakagawa, A., Tanaka, H., Yoneda, Y., and Tsukihara, T.
Crystallization and preliminary crystallographic analysis of the importin-b-SREBP-2 complex.
Acta Crystallogr., D59: 1866-1868 (2003)

88) Tajima, Y., Goto, K., Yoshida, M., Shinomiya, K., Sekimoto, T., Yoneda, Y., Miyazono, K., and Imamura, T.
CRM1-depemdemt nuclear export of Smurf1 is essential for negative regulation of TGF-b signaling by Smad7.
J. Biol. Chem., 278: 10716-10721 (2003)

87) Kametaka, A., Takagi, M., Hayakawa, T., Haraguchi, T., Hiraoka, Y., and Yoneda, Y.
Interaction of the chromatin compaction-inducing domain (LR domain) of Ki-67 antigen with HP1 proteins.
Genes Cells, 7: 1231-1242 (2002)

86) Miyamoto, Y., Hieda, M., Harreman, M.T., Fukumoto, M., Saiwaki, T., Hodel, A.E., Corbett, A.H., and Yoneda, Y.
Importin a can migrate into the nucleus in an importin b- and Ran-independent manner.
EMBO J., 21: 5833-5842 (2002)

85) Sugiyama, T., Shimizu, S., Matsuoka, Y., Yoneda, Y., and Tsujimoto, Y.
Activation of mitochondrial voltage-dependent anion channel by a pro-apoptotic BH3-only protein Bim.
Oncogene, 21: 4944-4956 (2002)

84) Kondo, Y., Kondoh, J., Hayashi, D., Ban, T., Takagi, M., Kamei, Y., Kim, J., and Yoneda. Y.
Molecular cloning of one isotype of human lamina-associated polypeptide 1s and a topological analysis using its deletion mutants.
Biochem. Biophys. Res. Commun., 294: 770-778 (2002)

83) Matsuoka, Yo., Matsuoka, Yu., Shibata, S., Yasuhara, N., and Yoneda, Y.
Identification of Ewing's sarcoma gene product as a glycoprotein using a monoclonal antibody which recognizes an immunodeterminant containing O-linked N-acetylglucosamine moiety.
Hybridoma and Hybridomics, 21: 233-236 (2002)

82) Matsuoka, Yo., Matsuoka, Yu., Shibata, S., and Yoneda, Y.
Bovine liver chromatin fraction contains actin polymerization activity inducing micronuclei formation when injected into prometaphase cultured cells.
Cell Struct. Funct., 27: 39-45 (2002)<

81) Matsuoka, Yu., Matsuoka, Yo., Shibata, S., Ban, T., Toratani, N., Shigekawa, M., Ishida, H., and Yoneda, Y.
A chromodomain-containing nuclear protein, MRG15 is expressed as a novel type of dendritic mRNA in neurons.
Neurosci. Res., 42: 299-308 (2002)

80) Miyamoto, Y., Kim, J., Yuba, S., and Yoneda, Y.
Genomic organization and chromosomal localization of the importin a1 gene in the mouse.
Gene, 288: 49-56 (2002)

79) Katahira, J., Straesser, K., Saiwaki, T., Yoneda, Y., and Hurt, E.
Complex formation between Tap and p15 affects binding to FG-repeat nucleoporins and nucleocytoplasmic shuttling.
J. Biol. Chem., 277: 9242-9246 (2002)

78) Shibata, S., Matsuoka, Y., and Yoneda, Y.
Nucleocytoplasmic transport of proteins and poly(A)+RNA at the reconstituted Tpr-less nuclei in living mammalian cells.
Genes Cells, 7: 421-434 (2002)

77) Kobayashi, M., Kishida, S., Fukui, A., Michiue, T., Miyamoto, Y., Okamoto, T., Yoneda, Y., Asashima, M., and Kikuchi, A.
Nuclear localization of duplin, a b-catenin-binding protein, is essential for its inhibitory activity on the Wnt signaling pathway.
J. Biol. Chem., 277: 5816-5822 (2002)

76) Haraguchi, T., Koujin, T., Segura-Totten, M., Lee, K. K., Matsuoka, Y., Yoneda, Y., Wilson, K. L., and Hiraoka, Y.
BAF is required for emerin assembly into the reforming nuclear envelope.
J. Cell Sci., 114: 4575-4585 (2001)

75) Takagi, M., Sueishi, M., Saiwaki, T., Kametaka, A., and Yoneda, Y.
A novel nucleolar protein, NIFK, interacts with the forkhead associated domain of Ki-67 antigen in mitosis.
J. Biol. Chem., 276: 25386-25391 (2001)

74) Hieda, M., Tachibana, T., Fukumoto, M., and Yoneda, Y.
Nuclear import of the U1A splicesome protein is mediated by importin a/b and Ran in living mammalian cells.
J. Biol. Chem., 276: 16824-16832 (2001)

73) Kurisaki, A., Kose, S., Yoneda, Y., Heldin, C.-H., and Moustakas, A.
Transforming growth factor-b induces nuclear import of Smad3 in an importin-b1 and Ran-dependent manner.
Mol. Biol. Cell, 12: 1079-1091 (2001)

72) Akakura, S., Yoshida, M., Yoneda, Y., and Horinouchi, S.
A role for Hsc70 in regulating nucleo-cytoplasmic transport of a temperature-sensitive p53 (p53Val135).
J. Biol. Chem., 276: 14649-14657 (2001)

71) Jiang, C.-J., Shoji, K., Matsuki, R., Baba, A., Inagaki, N., Ban, H., Iwasaki, T., Imamoto, N., Yoneda, Y., Deng, X.-W., and Yamamoto, N.
Molecular cloning of a novel importin a homologue from rice, by which constitutive photomorphogenic 1 (COP1) nuclear localization signal (NLS)-protein is preferentially nuclear imported.
J. Biol. Chem., 276: 9322-9329 (2001)

70) Nagoshi, E. and Yoneda, Y.
Dimerization of the sterol regulatory element-binding protein-2 via the helix-loop-helix-leucine zipper domain is prerequisite for its nuclear localization mediated by importin b.
Mol. Cell. Biol., 21: 2779-2789 (2001)

69) Shimizu, S., Matsuoka, Y., Shinohara, Y., Yoneda, Y., and Tsujimoto, Y.
Essential role of voltage-dependent anion channel in various forms of apoptosis in mammalian cells.
J. Cell Biol., 152: 237-250 (2001)<

68) Sueishi, M., Takagi, M., and Yoneda, Y.
The FHA domain of Ki-67 antigen interacts with a novel kinesin-like protein Hklp2.
J. Biol. Chem., 275: 28888-28892 (2000)

67) Lee, S. J., Imamoto, N., Sakai, H., Nakagawa, A., Kose, S., Koike, M., Yamamoto, M., Kumasaka, T., Yoneda, Y., and Tsukihara, T.
The adoption of a twisted structure of importin-b is essential for the protein-protein interaction required for nuclear transport.
J. Mol. Biol. 302: 251-64 (2000)

66) Takeda, K., Haque M. M., Nagoshi, E., Takemoto, M., Shimamoto, T., Yoneda, Y., and Yamanishi, K.
Characterization of human herpesvirus 7 U27 gene product and identification of its nuclear localization signal.
Virology 2000 Jul 5;272(2):394-401 (2000)

65) Tanabe, K., Tachibana, T., Yamashita, T., Che, Y.-H., Yoneda, Y., Ochi, T., Tohyama, M., and Kiyama, H.
The small GTP-binding protein TC10 promotes growth cone formation and nerve elongation in neuronal cells, and its transcription is induced during nerve regeneration in rat.
J. Neurosci., 20: 4138-4144 (2000)

64) Ikuta, T., Tachibana, T., Watanabe, J., Yoshida, M., Yoneda, Y., and Kawajiri, K.
Nucleocytoplasmic shuttling of the aryl hydrocarbon receptor.
FEBS Lett., 468: 171-175 (2000)

63) Tachibana, T., Hieda, M., Miyamoto, Y., Kose, S., Imamoto, N., and Yoneda, Y.
Recycling of importin a from the nucleus is suppressed by loss of RCC1 function in living mammalian cells.
Cell Struct. Funct., 25: 95-103 (2000)

62) Matsubae, M., Kurihara, T., Tachibana, T., Imamoto, N., and Yoneda, Y.
Characterization of the nuclear transport of a novel leucine-rich acidic nuclear protein-like protein.
FEBS Lett., 468: 171-175 (2000)

61) Haraguchi, T., Koujin, T., Kaneda, T., Tsutsumi, C., Imamoto, N., Akazawa, C., Sukegawa, J., Yoneda, Y., and Hiraoka, Y.
Live fluorescence imaging reveals early recruitment of emerin, LBR, HP1b and RanBP2 to reforming functional nuclear envelope.
J. Cell Sci., 113: 779-794 (2000)

60) Kose, S., Imamoto, N., and Yoneda, Y.
Distinct energy requirement for nuclear import and export of importin b in living cells.
FEBS Lett., 463: 327-330 (1999)

59) Ohshima, T., Nakajima, T., Oishi, T., Imamoto, N., Yoneda, Y., Fukamizu, A., and Yagami, K.
CRM1 mediates nuclear export of nonstructural protein 2 from parvovirus minute virus of mice.
Biochem. Biophys. Res. Commun., 264: 144-150 (1999)

58) Sahara, S., Aoto, M., Eguchi, Y., Imamoto, N., Yoneda, Y., and Tsujimoto, Y.
Acinus, a caspase-3-activated protein responsible for apoptotic chromatin condensation.
Nature, 401: 168-173 (1999)

57) Takagi, M., Matsuoka, Y., Kurihara, T., and Yoneda, Y.
Chmadrin: a novel Ki-67 antigen-related perichromosomal protein possibly implicated in higher order chromatin structure.
J. Cell Sci., 112: 2463-2472 (1999)

56) Nagoshi, E., Imamoto, N., Sato, R., and Yoneda, Y.
Nuclear import of sterol regulatory element-binding protein-2, a basic helix-loop-helix-leucine zipper (bHLH-Zip)-containing transcription factor occurs through the direct interaction of importin b with HLH-Zip.
Mol. Biol. Cell, 10: 2221-2233 (1999)

55) Yokoya, F., Imamoto, N., Tachibana, T., and Yoneda, Y.
b-Catenin can be transported into the nucleus in a Ran-unassisted manner.
Mol. Biol. Cell, 10: 1119-1131 (1999)

54) Kikuchi, N., Gohshi, T., Kawahire, S., Tachibana, T., Yoneda, Y., Isobe, T., Lim, C. R., Kohno, K., Ichimura, T., Omata, S., and Horigome, T.
Molecular shape and ATP binding activity of rat p50, a putative mammalian homologue of RuvB DNA helicase.
J. Biochem., 125: 487-494 (1999)

53) Kamei, Y., Yuba, S., Nakayama, T., and Yoneda, Y.
Three distinct classes of the a subunit of the nuclear pore-targeting complex (importin-a) are differentially expressed in adult mouse tissues.
J. Histochem. Cytochem., 47: 363-372 (1999)

52) Hieda, M., Tachibana, T., Yokoya, F., Kose, S., Imamoto, N., and Yoneda, Y.
A monoclonal antibody to the C-terminal acidic portion of Ran inhibits both the recycling of Ran and nuclear protein import in living cells.
J. Cell Biol., 144: 645-655 (1999)

51) Kose, S., Imamoto, N., Tachibana, T., Yoshida, M., and Yoneda, Y.
b-Subunit of nuclear pore-targeting complex (importin-b) can be exported from the nucleus in a Ran-independent manner.
J. Biol. Chem., 274: 3946-3952 (1999)

50) Matsuoka, Y., Takagi, M., Ban, T., Miyazaki, M., Yamamoto, T., Kondo, Y., and Yoneda, Y.
Identification and characterization of nuclear pore subcomplexes in mitotic extract of human somatic cells.
Biochem. Biophys. Res. Commun., 254: 417-423 (1999)

49) Tachibana, T., Hieda, M., and Yoneda, Y.
Up-regulation of nuclear protein import by nuclear localization signal sequences in living cells.
FEBS Lett., 442: 235-240 (1999)

48) Yamada, M., Tachibana, T., Imamoto, N., and Yoneda, Y.
Nuclear transport factor p10/NTF2 functions as a Ran-GDP dissociation inhibitor (Ran-GDI).
Curr. Biol., 8: 1339-1342 (1998)

47) Jiang, C.-J., Imamoto, N., Matsui, R., Yoneda, Y., and Yamamoto, N.
In vitro characterization of rice importin b1: molecular interaction with nuclear transport factors and mediation of nuclear protein import.
FEBS Lett., 437: 127-130 (1998)

46) Jiang, C.-J., Imamoto, N., Matsuki, R., Yoneda, Y., and Yamamoto, N.
Functional characterization of a plant importin a homologue: Nuclear localization signal (NLS)-selective binding and mediation of nuclear import of NLS-proteins in vitro.
J. Biol. Chem., 273: 24083-24087 (1998)

45) Matsusaka, T., Imamoto, N., Yoneda, Y., and Yanagida, M.
Mutations in fission yeast Cut15, an importin a homolog, lead to mitotic progression without chromosome condensation.
Curr. Biol. 8: 1031-1034 (1998)

44) Kudo, N., Wolff, B., Sekimoto, T., Schreiner, E. P., Yoneda, Y., Yanagida, M., Horinouchi, S., and Yoshida, M.
Leptomycin B inhibition of signal-mediated nuclear export by direct binding to CRM1.
Exp. Cell Res., 242: 540-547 (1998)

43) Nakamura, N., Ban, T., Yamaji, K., Yoneda, Y., and Wada, Y.
Localization of the apoptosis-inducing activity of lupus anticoagulant in an annexin V-binding antibody subset.
J. Clin. Invest., 101: 1951-1959 (1998)

42) Murai, T., Hanakawa, T., Sengoku, A., Ban, T., Yoneda, Y., Fujita, H., and Fujita, N.
Temporal lobe epilepsy in a genius of natural history: MRI volumetric study of postmortem brain.
Neurology, 50: 1373-1376 (1998)<

41) Ikuta, T., Eguchi, H., Tachibana, T., Yoneda, Y., and Kawajiri, K.
Nuclear localization and export signals of the human aryl hydrocarbon receptor.
J. Biol. Chem., 273: 2895-2904 (1998)

40) Sekimoto, T., Imamoto, N., Nakajima, K., Hirano, T., and Yoneda, Y.
Extracellular signal-dependent nuclear import of Stat1 is mediated by nuclear pore-targeting complex formation with NPI-1, but not Rch1.
EMBO J., 16: 7067-7077 (1997)

39) Kose, S., Imamoto, N., Tachibana, T., Shimamoto, T., and Yoneda, Y.
Ran-unassisted nuclear migration of a 97kDa component of nuclear pore-targeting complex.
J. Cell Biol., 139: 841-849 (1997)

38) Tsuji, L., Takumi, T., Imamoto, N., and Yoneda, Y.
Identification of novel homologues of mouse importin a, the a subunit of the nuclear pore-targeting complex, and their tissue-specific expression.
FEBS Lett., 416: 30-34 (1997)

37) Miyamoto, Y., Imamoto, N., Sekimoto, T., Tachibana, T., Seki, T., Tada, S., Enomoto, T., and Yoneda, Y.
Differential modes of nuclear localization signal (NLS) recognition by three distinct classes of NLS receptors.
J. Biol. Chem., 272: 26375-26381 (1997)

36) Eguchi, H., Ikuta, T., Tachibana, T., Yoneda, Y., and Kawajiri, K.
A nuclear localization signal of human aryl hydrocarbon receptor nuclear translocator/hypoxia-inducible factor 1b is a novel bipartite type recognized by the two components of nuclear pore-targeting complex.
J. Biol. Chem., 272: 17640-17647 (1997)

35) Kajikawa, H., Umemoto, M., Taira, E., Miki, N., Mishiro, Y., Kubo, T., and Yoneda, Y.
Expression of neurite outgrowth factor and gicerin during inner ear development and hair cell regeneration in the chick.
J. Neurocytol., 26: 501-509 (1997)

34) Yasuhara, N., Eguchi, Y., Tachibana, T., Imamoto, N., Yoneda, Y., and Tsujimoto, Y.
Essential role of active nuclear transport in apoptosis.
Genes Cells, 2: 55-64 (1997)

33) Kajikawa, H., Umemoto, M., Mishiro, Y., Sakagami, M., Kubo, T., and Yoneda, Y.
Expression of highly polysialylated NCAM (NCAM-H) in developing and adult chicken auditory organ.
Hearing Res., 103: 123-130 (1997)

32) Sekimoto, T., Nakajima, K., Tachibana, T., Hirano, T., and Yoneda, Y.
Interferon-g-dependent nuclear import of Stat1 is mediated by the GTPase activity of Ran/TC4.
J. Biol. Chem., 271: 31017-31020 (1996)

31) Tachibana, T., Hieda, M., Sekimoto, T., and Yoneda, Y.
Exogenously injected nuclear import factor p10/NTF2 inhibits signal-mediated nuclear import and export of proteins in living cells.
FEBS Lett., 397: 177-182 (1996)

30) Kurihara, T., Hori, M., Takeda, H., Inoue, M., and Yoneda, Y.
Partial purification and characterization of a protein kinase that is activated by nuclear localization signal peptides.
FEBS Lett., 380: 241-245 (1996)

29) Yoshida, K., Taga, T., Saito, M., Suematsu, S., Kumanogoh, A., Tanaka, T., Fujiwara, H., Hirata, M., Yamagami, T., Nakahata, T., Hirabayashi, T., Yoneda, Y., Tanaka, K., Wang, W.-Z., Mori, C., Shiota, K., Yoshida, N., and Kishimoto, T.
Targeted disruption of gp130, a common signal transducer for the interleukin 6 family of cytokines, leads to myocardial and hematological disorders.
Proc. Natl. Acad. Sci. USA, 93: 407-411 (1996)

28) Kawahire, S., Tachibana, T., Umemoto, M., Yoneda, Y., Imai, N., Saito, M., Ichimura, T., Omata, S., and Horigome, T.
Subcellular distribution and phosphorylation of the nuclear localization signal binding protein, NBP60.
Exp. Cell Res., 222: 385-394 (1996)

27) Shimamoto, T., Tanimura, T., Yoneda, Y., Kobayakawa, Y., Sugasawa, K., Hanaoka, F., Oka, M., Okada, Y., Tanaka, K., and Kohno, K.
Expression and functional analyses of the Dxpa gene, the Drosophila homolog of the human excision repair gene XPA.
J. Biol. Chem., 270: 22452-22459 (1995)

26) Fukuda, M., Gotoh, Y., Tachibana, T., Dell, K., Hattori, S., Yoneda, Y., and Nishida, E.
Induction of neurite outgrowth by MAP kinase in PC12 cells.
Oncogene, 11: 239-244 (1995)

25) Imamoto, N., Shimamoto, T., Kose, S., Takao, T., Tachibana, T., Matsubae, M., Sekimoto, T., Shimonishi, Y., and Yoneda, Y.
The nuclear pore-targeting complex binds to nuclear pores after association with a karyophile.
FEBS Lett., 368: 415-419 (1995)

24) Terada, K., Ohtsuka, K., Imamoto, N., Yoneda, Y., and Mori, M. Role of heat shock cognate 70 protein in import of ornithine transcarbamylase precursor into mammalian mitochondria.
Mol. Cell. Biol., 15: 3708-3713 (1995)

23) Umemoto, M., Sakagami, M., Fukazawa, K., Ashida, K., Kubo, T., Senda, T., and Yoneda, Y.
Hair cell regeneration in the chick inner ear following acoustic trauma: ultrastructural and immunohistochemical studies.
Cell Tissue Res., 281: 435-443 (1995)

22) Imamoto, N., Shimamoto, T., Takao, T., Tachibana, T., Kose, S., Matsubae, M., Sekimoto, T., Shimonishi, Y., and Yoneda, Y.
In vivo evidence for involvement of a 58 kDa component of nuclear pore-targeting complex in nuclear protein import.
EMBO J., 14: 3617-3626 (1995)

21) Imamoto, N., Tachibana, T., Matsubae, M., and Yoneda, Y.
A karyophilic protein forms a stable complex with cytoplasmic components prior to nuclear pore binding.
J. Biol. Chem., 270: 8559-8565 (1995)

20) Tanaka, T., Akira, S., Yoshida, K., Umemoto, M., Yoneda, Y., Shirafuji, N., Fujiwara, H., Suematsu, S., Yoshida, N., and Kishimoto, T.
Targeted disruption of the NF-IL6 gene discloses its essential role in bacteria killing and tumor cytotoxicity by macrophages.
Cell, 80: 353-361 (1995)

19) Tachibana, T., Imamoto, N., Seino, H., Nishimoto, T., and Yoneda, Y.
Loss of RCC1 leads to suppression of nuclear protein import in living cells.
J. Biol. Chem., 269: 24542-24545 (1994)

18) Kato, K., Yoneda, Y., Okada, Y., Kiyama, H., and Shiosaka, S.
Gene transfer and the expression of a foreign gene in vivo in post-mitotic neurons of the adult rat brain using the hemagglutinating virus of Japan-liposome method.
Mol. Brain Res., 25: 359-363 (1994)

17) Matsuoka, Y., Takechi, S., Nakayama, T., and Yoneda, Y.
Exogenous histone H1 injection into mitotic cells disrupts synchronous progression of mitotic events by delaying chromosome condensation.
J. Cell Sci., 107: 693-701 (1994)

16) Kato, K., Dohi, Y., Yoneda, Y., Yamamura, K., Okada, Y., and Nakanishi, M.
Use of the hemagglutinating virus of Japan (HVJ)-liposome method for analysis of infiltrating lymphocytes induced by hepatitis B virus gene expression in liver tissue.
Biochim. Biophys. Acta, 1182: 283-290 (1993)

15) Okuno, Y., Imamoto, N., and Yoneda, Y.
70-kD heat-shock cognate protein colocalizes with karyophilic proteins into the nucleus during their transport in vitro.
Exp. Cell Res., 206: 134-142 (1993)

14) Imamoto, N., Matsuoka, Y., Kurihara, T., Kohno, K., Miyagi, M., Sakiyama, F., Okada, Y., Tsunasawa, S., and Yoneda, Y.
Antibodies against 70-kD heat shock cognate protein inhibit mediated nuclear import of karyophilic proteins.
J. Cell Biol., 119: 1047-1061 (1992)

13) Yoneda, Y., Semba, T., Kaneda, Y., Noble, R. L., Matsuoka, Y., Kurihara, T., Okada, Y., and Imamoto, N.
A long synthetic peptide containing a nuclear localization signal and its flanking sequences of SV40 T-antigen directs the transport of IgM into the nucleus efficiently.
Exp. Cell Res., 201: 313-320 (1992)

12) Kido, M., Yoneda, Y., Nakanishi, M., Uchida, T., and Okada, Y.
Escherichia coli RecA protein modified with a nuclear location signal binds to chromosomes in living mammalian cells.
Exp. Cell Res., 198: 107-114 (1992)

11) Yoneda, A., Yoneda, Y., Kaneda, Y., Hayes, H., Uchida, T., and Okada, Y.
Monoclonal antibodies specific for human chromosome 5 obtained with a monochromosomal hybrid can be used to sort out cells containing the chromosome with a FACS.
Chromosoma, 100: 187-192 (1991)

10) Imamoto-Sonobe, N., Matsuoka, Y., Semba, T., Okada, Y., Uchida, T., and Yoneda, Y.
A protein recognized by antibodies to Asp-Asp-Asp-Glu-Asp shows specific binding activity to heterogeneous nuclear transport signals.
J. Biol. Chem., 265: 16504-16508 (1990)

9) Kim, J., Adachi, T., Yoneda, Y., and Okada, Y.
Fusion of Madin-Darby canine kidney cells by HVJ (Sendai virus): absence of direct association of virus particles with the site of membrane fusion.
Eur. J. Cell Biol., 51: 128-134 (1990)

8) Miwatani, H., Yoneda, Y., Maki, H., Kaneda, Y., and Uchida, T.
Secretion of Mr 46,000 protein from human hepatoma cells treated with tumor promoters is regulated by c-myc gene expression.
Cell Struct. Funct., 14: 183-192 (1989)

7) Yoneda, Y., Imamoto-Sonobe, N., Matsuoka, Y., Iwamoto, R., Kiho, Y., and Uchida, T.
Antibodies to Asp-Asp-Glu-Asp can inhibit transport of nuclear proteins into the nucleus.
Science, 242: 275-278 (1988)

6) Imamoto-Sonobe, N., Yoneda, Y., Iwamoto, R., Sugawa, H., and Uchida, T.
ATP-dependent association of nuclear proteins with isolated rat liver nuclei.
Proc. Natl. Acad. Sci. USA, 85: 3426-3430 (1988)

5) Yoneda, Y., Imamoto-Sonobe, N., Yamaizumi, M., and Uchida, T.
Reversible inhibition of protein import into the nucleus by wheat germ agglutinin injected into cultured cells.
Exp. Cell Res., 173: 586-595 (1987)

4) Yoneda, Y., Arioka, T., Imamoto-Sonobe, N., Sugawa, H., Shimonishi, Y., and Uchida, T.
Synthetic peptides containing a region of SV40 large T-antigen involved in nuclear localization direct the transport of proteins into the nucleus.
Exp. Cell Res., 170: 439-452 (1987)

3) Hara, Y., Yoneda, Y., Uchida, T., and Okada, Y.
Some properties of IgG against diphtheria toxin synthesized in Xenopus oocytes containing mRNA from hybridoma.
Biochim. Biophys. Acta, 825: 188-198 (1985)

2) Sugawa, H., Uchida, T., Yoneda, Y., Ishiura, M., and Okada, Y.
Large macromolecules can be introduced into cultured mammalian cells using erythrocyte membrane vesicles.
Exp. Cell Res., 159: 410-418 (1985)

1) Yoneda, Y., Fujiki, H., Moore, R. E., and Uchida, T.
Induced secretion of a Mr 46,000 protein by cultured human hepatoma cells treated with tumor promoters.
Cancer Res., 45: 2363-2368 (1985)


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