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NewTwo of our professors, Profs. Tadamitsu Kishimoto and Toshio Hirano, along with Prof. Charles Dinarello, (USA) are awarded The Crafoord Prize 2009 by The Royal Swedish Academy of Sciences.
>> Details of the award (PDF)
>> Award Ceremony, Symposium and Lectures, May 11-13, 2009 in Stockholm/Lund, Sweden (PDF)
Osaka University Global COE Summer School and IBRO-APRC Advanced School 2008 was held July 14 - July 25, 2008.
Job openings at FBS: One Tenured Professor, Two Tenure-track Associate Professors (Application deadline: October 31, 2007)
Graduate School of Frontier Bisciences has been selected as one of the Global COE sites (A07) for our program "System Dynamics of Biological Function" (program leader: Toshio Yanagida) - June 25, 2007.
Summary from the "Report on the Two Papers Suspected of Involving Scientific Misconduct” by the Scientific Ethics and Research Conduct Committee at the Graduate School of Frontier Biosciences, Osaka University, finalized on September 21, 2006 and publicly released on September 22, 2006.
## An English translation (PDF format 113KB) ##
(Full Report in Japanese is at this link)
Join our Ph.D. program: Application information for Master's degree holders (Application deadline: Jan. 12, 2007) -- Closed.
COE Summer School 2006 (July 3 - July 14): -- Completed.
Message from the Dean (April, 2006)
Alternative Admission Process Based on GRE+TOEFL for April 2008 Enrollement
COE21 Seminar Schedule and Reports
Web Site Uploaded (Sep. 5, 2003)

Top News
Four of our professors, Toshio Hirano, Tadamitsu Kishimoto, Kiyoji Tanaka, and Shigekazu Nagata have been selected in the ISIHighlyCited.com's citation ranking.
   
 
image NewFGF8 Signaling Regulates Growth of Midbrain Dopaminergic Axons by Inducing Semaphorin 3F
The Journal of Neuroscience, April 1, 2009, 29(13):4044-4055
)

Neuroscience Laboratories, Developmental and Functional Neuroscience Group (Prof. Murakami)
image_1_140 NewHepatic Interleukin-7 Expression Regulates T Cell Responses
Immunity(Volume 30, 447-457, 2009)


Laboratory of Developmental Immunology (Prof. Hirano)
image_top NewSpinogenesis and pruning scales across functional hierarchies
Journal of Neuroscience March 11, 2009, 29(10):3271-3275.
)

Neurocience Laboratories, Cognitive Neuroscience Group (Prof. Fujita)
NewRandom Walk Behavior of Migrating Cortical Interneurons in the Marginal Zone: Time-Lapse Analysis in Flat-Mount Cortex
Journal of Neuroscience, February 4, 2009, 29(5):1300-1311
)

Neuroscience Laboratories, Developmental and Functional Neuroscience Group (Prof. Murakami)
NewInvolvement of linear polyubiquitylation of NEMO in NF-κB activation
Nature Cell Biology 11: 123-132, 2009 (Vol 11. No.2 February, 2009
)

Biomolecular Networks Laboratories, Cell Biology and Metabolism Group (Prof. Iwai)
Method to control the coupling function using multilinear feedback
Physical Review E 78, 056210 (Nov. 2008
)

Nonequilibrium Physics Group (Prof. Kinoshita)
Interleukin-17 Promotes Autoimmunity by Triggering a Positive-Feedback Loop via Interleukin-6 Induction.
Immunity, 7: 971 - 977 (2006) (Vol 29, 628-636, 17 October 2008)


Laboratory of Developmental Immunology (Prof. Hirano)
Fluctuation Analysis of Mechanochemical Coupling Depending on the Type of Biomolecular Motors
Physical Review Letters & Molecular Biology PRL 101,128103(2008), 19 SEPTEMBER 2008


Soft Biosystem Laboratory
(Prof. Yanagida)
IQGAP3 regulates cell proliferation through the Ras/ERK signalling cascade
Nature Cell Biology (published online 6 July 2008)

Biological Science Laboratory (Prof. Tsukita)
Distinct roles of the Flil ATPase and proton motive force in bacterial flagellar rotein exprt
Nature Vol 451 | 24 January(2008)


Protonic NanoMachine Laboratory
(Prof. Namba)
Haemodynamics determined by a genetic programme govern asymmetric development of the aortic arch.
Nature 450: 285-288 (2007)

Developmental Genetics Laboratory
(Prof. Hamada)
Myosin-V makes two brownian 90 degrees rotations per 36-nm step.
Nature Structrural & Molecular Biology 14(10):968-973 (2007)


Soft Biosystem Laboratory
(Prof. Yanagida)
Molecular Cell, 26 (2): 231-243 (27 April 2007).

Human Cell Biology Laboratory
(Prof. Tanaka)
Nature Cell Biology, (Published online: December 3, 2006)

Laboratory of Stem Cell Pathology
(Prof. Nakano)
Nature Cell Biology, (Published online: December 10, 2006).

Biomolecular Dynamics Laboratory
(Prof. Yoneda)
Nature, 443:998-1002 (2006) (26 Oct. 2006)
Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages.

Laboratory of Genetics (Prof. Nagata)
Nature Immunology, 7: 971 - 977 (2006) (Published online: 6 August 2006; | doi:10.1038/ni1373)
Toll-like receptor mediated regulation of zinc homeostasis influences dendritic cell function.

Laboratory of Developmental Immunology (Prof. Hirano)
Neuron, 50, 841-853 (2006), (June 15th, 2006)
PFGF as a Target-Derived Chemoattractant for Developing Motor Axons Genetically Programmed by the LIM Code.

Cellular and Molecular Neurobiology Group
Physical Review Letters, 96, 194101 (May 2006)
Determination of a Coupling Function in Multicoupled Oscillators.

Nonequilibrium Physics Group (Prof. Kinoshita)
Nature Chemical Biology 1, 346-351 (2005)
Entropy rectifies the Brownian steps of kinesin.

Soft Biosystem Laboratory
(Prof. Yanagida)
Nature, 437:754-8(Sep29 2005)
Phosphatidylserine-dependent engulfment by macrophages of nuclei from erythroid precursor cells.

Laboratory of Genetics (Prof. Nagata)
Cell ,121(3): 387-400 (6 May 2005)
Different mutation signatures in DNA polymerase {eta}- and MSH6-deficient mice suggest separate roles in antibody diversification.

Cellular Biology Laboratory(Prof. Hanaoka)
Human Cell Biology Laboratory(Prof. Tanaka)
Nature Genetics, 37(2):171-176 (9 Feb 2005)
Monoallelic yet combinatorial expression of variable exons of the CNR/Protocadherin-a gene cluster in single neurons.

KOKORO-Biology Laboratory(Prof. Yagi)
Nature Immunology,6(1):49-56(Jan 2005).
Lethal anemia caused by interferon-β produced in mouse embryos carrying undigested DNA.

Laboratory of Genetics(Prof. Nagata)
Nature, 431(7012): 1062-8 (28 Oct 2004).
Structure of the bacterial flagellar hook and implication for the molecular universal joint mechanism.

Protonic NanoMachine Laboratory
(Prof. Namba)
Science, 304: 1147-1150 (21 May 2004)
Autoimmune disease and impaired uptake of apoptotic cells in MFG-E8-deficient mice.

Laboratory of Genetics (Prof. Nagata)
Nature,429(6989):298-302(20 May 2004).
Zinc transporter LIVI controls epithelial-mesenchymal transition?in zebrafish gastrula organizer.

Laboratory of Developmental Immunology
(Prof. Hirano)
Nature, 428: 387-392 (2004)
Nodal antagonists regulate formation of the anteroposterior axis of the mouse embryo.

Developmental Genetics Laboratory
(Prof. Hamada)
Science, 302: 1571-1575 (2003)
The structure of importin-beta bound to SREBP-2: Insights into nuclear import of a transcription factor.
Biomolecular Dynamics Laboratory
(Prof. Yoneda)
Nature, 424: 1071-1074 (2003)
Nuclear cataract caused by a lack of DNA degradation in the mouse eye lens.

Laboratory of Genetics
(Prof. Nagata)
Nature, 424: 643-650 (2003)
Complete atomic model of the bacterial flagellar filament by electron cryomicroscopy.

Protonic NanoMachine Laboratory
(Prof. Namba)
   
   
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