Graduate School of Frontier Biosciences, Osaka University

Japanese

Research Highlight

Date Description PubMed Laboratory
2014-02 Pih1d3 is required for cytoplasmic preassembly of axonemal dynein in mouse sperm

Fenglan Dong (1), Kyosuke Shinohara (1), Yanick Botilde (1), Ryo Nabeshima (1), Yasuko Asai (1), Akemi Fukumoto (1), Toshiaki Hasegawa (2), Moe Matsuo (3), Hiroyuki Takeda (3), Hidetaka Shiratori (1), Tetsuya Nakamura (1), and Hiroshi Hamada (1)

  1. Developmental Genetics Group, Graduate School of Frontier Biosciences, Osaka University, and Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Corporation (JST), 1-3 Yamada-oka, Suita, Osaka 565-0871, Japan
  2. Research Center for Ultrahigh Voltage Electron Microscopy, Osaka University, 7-1 Mihogaoka, Ibaraki, Osaka 567-0047, Japan
  3. Department of Biological Sciences, Graduate School of Science, University of Tokyo, 7-3-1 Hongoh, Bunkyo-ku, Tokyo 113-0033, Japan


J Cell Biol 204, 203-213 (2014)
24421334
2014-02 Two appendages homologous between basal bodies and centrioles are formed using distinct Odf2 domains

Kazuhiro Tateishi (1), Yuji Yamazaki (1), Tomoki Nishida (2), Shin Watanabe (1), Koshi Kunimoto (3), Hiroaki Ishikawa (4), Sachiko Tsukita (1)*

  1. Laboratory of Biological Science, Graduate School of Frontier Biosciences and Graduate School of Medicine, Osaka University, Osaka 565-0871, Japan
  2. Research Center for Ultra-high Voltage Electron Microscopy, Osaka University, Osaka 567-0047, Japan
  3. Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305
  4. Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94158

K. Tateishi and Y. Yamazaki contributed equally to this paper.
*: Corresponding author

J Cell Biol 203, 417-425 (2013)
24189274 Biological Science Group 〈Prof. Tsukita〉
2014-01 Nano-Analysis of DNA Conformation Changes Induced by Transcription Factor Complex Binding Using Plasmonic Nanodimers

Hiroyuki Morimura (1), Shin-Ichi Tanaka (2), Hidekazu Ishitobi (1, 2), Tomoyuki Mikami (2), Yusuke Kamachi (2), Hisato Kondoh (2), Yasushi Inouye (1, 2, 3)

  1. Department of Applied Physics, 2-1 Yamada-oka, Suita, Osaka 565-0871, Japan
  2. Graduate School of Frontier Biosciences, 1-3 Yamada-oka, Suita, Osaka 565-0871, Japan
  3. Photonics Advanced Research Center, Osaka University, 2-1 Yamada-oka, Suita, Osaka 565-0871, Japan


ACS Nano 7, 10733-10740 (2013)
24195575 Nano Biophotonics Group 〈Prof. Inouye〉
2013-12 The association of microtubules with tight junctions is promoted by cingulin phosphorylation by AMPK

Tomoki Yano (1), Takeshi Matsui (2), Atsushi Tamura (1), Masami Uji (1), Sachiko Tsukita (1)

  1. Laboratory of Biological Science, Graduate School of Frontier Biosciences and Graduate School of Medicine, Osaka University, Suita 565-0871, Japan
  2. Laboratory for Skin Homeostasis, RCAI, RIKEN Center for Integrative Medical Sciences, Tsurumi-ku, Yokohama 230-0045, Japan


J Cell Biol 203, 605-614 (2013)
Biological Science Group 〈Prof. Tsukita〉
2013-11 Involvement of TrkB- and p75NTR-signaling pathways in two contrasting forms of long-lasting synaptic plasticity

Shigeo Sakuragi, Keiko Tominaga-Yoshino, Akihiko Ogura
(Graduate School of Frontier Biosciences, and Department of Physics, Osaka University 1-3 Yamadaoka, Suita, Osaka 565-0871, Japan)

Sci Rep 3, 3185 (2013)
24212565 Synaptic Plasticity Group 〈Assoc. Prof. Tominaga-Yoshino〉
2013-11 Epigenetically induced paucity of histone H2A.Z stabilizes fission yeast ectopic centromeres

Yuki Ogiyama, Yuko Ohno, Yoshino Kubota, Kojiro Ishii
(Graduate School of Frontier Biosciences, Osaka University 1-3 Yamadaoka, Suita, Osaka 565-0871, Japan)


Nat Struct Mol Biol 20, 1397-1406 (2013)
See also "Cover"
24186062
2013-10 An investigation of electron-phonon coupling via phonon dispersion measurements in graphite using angle-resolved photoelectron spectroscopy

Shin-ichiro Tanaka (1), Masaharu Matsunami (2, 3), Shin-ichi Kimura (2, 3, 4)
  1. The Institute of Industrial and Scientific Research, Osaka University, 567-0047 Mihogaoka, Ibaraki, Osaka, Japan
  2. UVSOR Facility, Institute for Molecular Science, Okazaki 444-8585, Japan
  3. School of Physical Sciences, The Graduate University for Advanced Studies, Okazaki 444-8585, Japan
  4. Graduate School of Frontier Biosciences, and Department of Physics, Osaka University 1-3 Yamadaoka, Suita, Osaka 565-0871, Japan


Sci. Rep. (2013) online
Photophysics Laboratory 〈Prof. Kimura〉
2013-10 Relationship between the local structure of orientation map and the strength of orientation tuning of neurons in monkey V1: A 2-photon calcium imaging study

Koji Ikezoe (1, 2), Yoshiya Mori (1), Kazuo Kitamura (3, 4), Hiroshi Tamura (1, 2, 3), Ichiro Fujita (1, 2, 3)

  1. Laboratory for Cognitive Neuroscience, Graduate School of Frontier Biosciences, Osaka University, Toyonaka, Osaka, 560-8531, Japan
  2. Center for Information and Neural Networks (CiNet), Osaka University and National Institute of Information and Communications Technology, Suita, Osaka, 565-0871, Japan
  3. Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency, Kawaguchi, Saitama, 332-0012, Japan
  4. Department of Neurophysiology, Graduate School of Medicine, University of Tokyo, Bunkyo, Tokyo, 113-0033, Japan


J Neurosci 33, 16818-16827 (2013)
24133282 Cognitive Neuroscience Group 〈Prof. Fujita〉
2013-10 Recruitment of The Autophagic Machinery to Endosomes during Infection is Mediated by Ubiquitin

Naonobu Fujita (1, 2), Eiji Morita (3), Takashi Itoh (8), Atsushi Tanaka (2), Megumi Nakaoka (2), Yuki Osada (1), Tetsuo Umemoto (2), Tatsuya Saitoh (4, 5), Hitoshi Nakatogawa (7), Shouhei Kobayashi (9), Tokuko Haraguchi (9), Jun-Lin Guan (10), Kazuhiro Iwai (11), Fuminori Tokunaga (12), Kazunobu Saito (6), Koutaro Ishibashi (8), Shizuo Akira (4, 5), Mitsunori Fukuda (8), Takeshi Noda (1, 2) & Tamotsu Yoshimori (1, 2)
  1. Department of Genetics, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan
  2. Laboratory of Intracellular Membrane Dynamics, Graduate school of Frontier Biosciences, Osaka University, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan
  3. Department of Molecular Virology, Research Institute for Microbial Diseases, Osaka University, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan
  4. Department of Host Defense, WPI Immunology Frontier Research Center, Osaka University, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan
  5. Department of Host Defense, Research Institute for Microbial Disease, Osaka University, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan
  6. Core Instrumentation Facility, Research Institute for Microbial Disease, Osaka University, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan
  7. Frontier Research Center, Tokyo Institute of Technology, Yokohama 226-8503, Japan
  8. Department of Developmental Biology and Neurosciences, Graduate School of Life Sciences, Tohoku University, Sendai, Miyagi 980-8578, Japan
  9. Advance ICT Research Institute Kobe, National Institute of Information and Communications Technology, Kobe 651-2492, Japan
  10. Department of Internal Medicine–MMG, University of Michigan Medical School, Ann Arbor, MI 48109
  11. Department of Molecular and Cellular Physiology, Graduate School of Medicine, Kyoto University, Yoshida-konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan
  12. Institute for Molecular and Cellular Regulation, Gunma University, 3-39-15 Showa-machi, Maebashi, Gunma 371-8512, Japan


J Cell Biol (2013)
See also In This Issue
Laboratory of Intracellular Membrane Dynamics 〈Prof. Yoshimori〉
2013-09 2,4,6-Trichloroanisole is a potent suppressor of olfactory signal transduction

Hiroko Takeuchi (1), Hiroyuki Kato (2), Takashi Kurahashi (1)

  1. Graduate school of Frontier Biosciences, Osaka University
  2. Daiwa Can Company



PNAS (2013) Published online before print September 16, 2013
See also Article Highlights
24043819 Physiological Laboratory 〈Prof. Kurahashi〉
2013-08 Genetically encoded system to track histone modification in vivo.

Yuko Sato (1, 2), Masanori Mukai (3), Jun Ueda (4), Michiko Muraki (5), Timothy J. Stasevich (1), Naoki Horikoshi (6), Tomoya Kujirai (6), Hiroaki Kita (3), Taisuke Kimura (3), Seiji Hira (3), Yasushi Okada (7), Yoko Hayashi-Takanaka (1, 2), Chikashi Obuse (8), Hitoshi Kurumizaka (6), Atsuo Kawahara (5), Kazuo Yamagata (4), Naohito Nozaki (9) & Hiroshi Kimura (1, 2)

  1. Graduate School of Frontier Biosciences, Osaka University, Suita. 565-0871, Japan
  2. JST, CREST, Suita. 565-0871, Japan
  3. Faculty of Science and Engineering and Graduate School of Natural Science, Konan University, Okamoto, Higashinada, Kobe 658-8501, Japan
  4. Research Institute for Microbial Diseases, Osaka University, Suita, 565-0871, Japan
  5. Laboratory for Cardiovascular Molecular Dynamics, Riken Quantitative Biology Center (QBiC), Suita, Osaka 565-0874
  6. Graduate School of Advanced Science and Engineering, Waseda University, Tokyo 162-8480, Japan
  7. Laboratory for Cell Polarity Regulation, Riken Quantitative Biology Center (QBiC), Suita, Osaka 565-0874
  8. Graduate School of Life Science, Hokkaido University, Sapporo. 001-0021, Japan
  9. Mab Institute Inc., Sapporo. 001-0021, Japan


Sci Rep 3, 2436 (2013)
23942372 Nuclear Dynamics Group 〈Prof. Hiraoka〉
2013-08 Autophagy sequesters damaged lysosomes to control lysosomal biogenesis and kidney injury

Ikuko Maejima (1, 8), Atsushi Takahashi (2), Hiroko Omori (3), Tomonori Kimura (2), Yoshitsugu Takabatake (2), Tatsuya Saitoh (4), Akitsugu Yamamoto (5), Maho Hamasaki (1), Takeshi Noda (6), Yoshitaka Isaka (2) and Tamotsu Yoshimori (1, 7, 8)

  1. Department of Genetics, Graduate School of Medicine, Osaka University, Osaka, Japan
  2. Department of Geriatric Medicine and Nephrology, Graduate School of Medicine, Osaka University, Osaka, Japan
  3. Research Institute for Microbial Diseases, Osaka University, Osaka, Japan
  4. Laboratory of Host Defense, WPI Immunology Frontier Research Center (IFReC), Osaka University, Osaka, Japan
  5. Faculty of Bioscience, Nagahama Institute of BioScience and Technology, Shiga, Japan
  6. Center for Frontier Oral Science, Graduate School of Dentistry, Osaka University, Osaka, Japan
  7. Laboratory of Intracellular Membrane Dynamics, Graduate School of Frontier Biosciences, Osaka University, Osaka, Japan
  8. Japan Science and Technology Agency CREST, Tokyo, Japan


EMBO J (2013) in press
23921551 Laboratory of Intracellular Membrane Dynamics 〈Prof. Yoshimori〉
2013-07 Importin Alpha Subtypes Determine Differential Transcription Factor Localization in Embryonic Stem Cells Maintenance

Noriko Yasuhara (1, 7, *), Ryosuke Yamagishi (6, 7), Yoshiyuki Arai (2), Rashid Mehmood (3), Chihiro Kimoto (3), Toshiharu Fujita (3), Kenichi Touma (3), Azumi Kaneko (3), Yasunao Kamikawa (3), Tetsuji Moriyama (3), Toshio Yanagida (2, 4), Hiroki Kaneko (6, *), Yoshihiro Yoneda (1, 3, 5)

  1. Department of Biochemistry, Graduate School of Medicine, Graduate School of Frontier Biosciences, Osaka University
  2. Soft Biosystem Group, Graduate School of Frontier Biosciences, Osaka University
  3. Biomolecular Dynamics Group, Graduate School of Frontier Biosciences, Osaka University
  4. Immunology Frontier Research Center, Graduate School of Frontier Biosciences, Osaka University
  5. JST-CREST, Graduate School of Frontier Biosciences, Osaka University
  6. Department of Integrated Sciences in Physics and Biology, College of Humanities and Sciences, Nihon University

*These authors contributed equally to this work.

Dev Cell 26, 123-135
23906064
2013-06 Dendritic spine dynamics in synaptogenesis after repeated LTP inductions: Dependence on pre-existing spine density.

Yuki Oe (1, 2), Keiko Tominaga-Yoshino (1), Sho Hasegawa (1) & Akihiko Ogura (1)

  1. Department of Neuroscience, Osaka University Graduate School of Frontier Biosciences, Yamadaoka 1-3, Suita 565-0871 Osaka, Japan
  2. Current address: RIKEN Brain Science Institure, Hirosawa 2-1, Wako 351-0198 Saitama, Japan


Scientific Reports 3, 1957 (2013)
23739837 Synaptic Plasticity Group 〈Assoc. Prof. Tominaga-Yoshino〉
2013-05 The four-transmembrane protein IP39 of Euglena forms strands by a trimeric unit repeat

Hiroshi Suzuki (1, *), Yasuyuki Ito (2, 3, *), Yuji Yamazaki (2), Katsuhiko Mineta (4), Masami Uji (2), Kazuhiro Abe (1), Kazutoshi Tani (1), Yoshinori Fujiyoshi (1) & Sachiko Tsukita (2)

  1. Cellular and Structural Physiology Institute (CeSPI), Nagoya University, Nagoya 464-8601, Japan.
  2. Laboratory of Biological Science, Graduate School of Frontier Biosciences and Graduate School of Medicine, Osaka University, Suita 565-0871, Japan.
  3. Research Fellow of the Japan Society for the Promotion of Science.
  4. Graduate School of Information Science and Technology, Hokkaido University, Kita, Sapporo, Hokkaido 060-0814, Japan.

*These authors contributed equally to this work.

Nat Commun 4, 1766 (2013)
23612307 Biological Science Group 〈Prof. Tsukita〉
2013-05 Cancelling prism adaptation by a shift of background: a novel utility of allocentric coordinates for extracting motor errors

Motoaki Uchimura (1, 2, 4), Shigeru Kitazawa (1, 2, 3, 4)
  1. Dynamic Brain Network Laboratory, Graduate School of Frontier Biosciences, Osaka University
  2. Department of Brain Physiology, Graduate School of Medicine, Osaka University
  3. Center for Information and Neural Networks (CiNet), National Institute of Information and Communications Technology, and Osaka University
  4. Department of Neurophysiology, Graduate School of Medicine, Juntendo University


J Neurosci 33, 7595-7602 (2013)
23616564 Dynamic Brain Network Laboratory 〈Prof. Kitazawa〉