Graduate School of Frontier Biosciences, Osaka University

Japanese

Research Highlight

Date Description PubMed Laboratory
2012-03 Neural activity in cortical area V4 underlies fine disparity discrimination

Shiozaki HM, Tanabe S, Doi T, Fujita I

J Neurosci 32, 3830-3841 (2012)
22423103 Cognitive Neuroscience Group 〈Prof. Fujita〉
2012-02 The structure of a type III secretion needle at 7-Å resolution provides insights into its assembly and signaling mechanisms

Takashi Fujii (1), Martin Cheung (2), Amandine Blanco (2), Takayuki Kato (1), Ariel J. Blocker (2), Keiichi Namba (1, 3)
  1. Graduate School of Frontier Biosciences, Osaka University, 1-3 Yamadaoka, Suita, Osaka 565-0871, Japan
  2. Schools of Cellular and Molecular Medicine and Biochemistry, Medical Sciences Building, University of Bristol, University Walk, Bristol BS8 1TD, United Kingdom
  3. Riken Quantitative Biology Center, 1-3 Yamadaoka, Suita, Osaka 565-0871, Japan


Proc Natl Acad Sci USA 109, 4461-4466 (2012)
22388746 Protonic NanoMachine Group 〈Prof. Namba〉
2012-02 Coordinated Ciliary Beating Requires Odf2-Mediated Polarization of Basal Bodies via Basal Feet

Koshi Kunimoto (1), Yuji Yamazaki (1,*), Tomoki Nishida (2,*), Kyosuke Shinohara (3,*), Hiroaki Ishikawa (4,*), Toshiaki Hasegawa (2), Takeshi Okanoue (5), Hiroshi Hamada (3), Tetsuo Noda (6), Atsushi Tamura (1), Shoichiro Tsukita (7) and Sachiko Tsukita (1,§)
  1. Laboratory of Biological Science, Graduate School of Frontier Biosciences and Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan.
  2. Research Center for Ultra-high Voltage Electron Microscopy, Osaka University, 7-1 Mihogaoka, Ibaraki, Osaka 567-0047, Japan.
  3. Developmental Genetics Group, Graduate School of Frontier Biosciences, Osaka University and CREST, Japan Science and Technology Corporation (JST), 1-3 Yamadaoka, Suita, Osaka 565-0871, Japan.
  4. Department of Biochemistry and Biophysics, University of California, San Francisco, CA94143, USA
  5. Department of Hepatology, Saiseikai Suita Hospital, Osaka, Japan.
  6. Department of Cell Biology, Cancer Institute of Japanese Foundation for Cancer Research, 3-10-6 Ariake, Koto-ku, Tokyo 135-8550,Japan.
  7. Department of Cell Biology, Faculty of Medicine, Kyoto University, Yoshida-Konoe, Kyoto 606-8315, Japan.

* : These authors nearly equally contribute to this work from different directions.
§ : Corresponding author.

Cell 148, 189-200 (2012)
22265411 Biological Science Group 〈Prof. Tsukita〉
2012-02 Pigment Pattern Formation by Contact-Dependent Depolarization

Inaba M, Yamanaka H, Kondo S

Science 335, 677 (2012)
22323812 Laboratory of Pattern Formation 〈Prof. Kondo〉
2012-02 Regional Neural Activation Defines a Gateway for Autoreactive T Cells to Cross the Blood-Brain Barrier

Yasunobu Arima (1), Masaya Harada (1), Daisuke Kamimura (1), Jin-Haeng Park (1), Fuminori Kawano (2), Fiona E. Yull (3), Tadafumi Kawamoto (5), Yoichiro Iwakura (6), Ulrich A.K. Betz (7), Gabriel Márquez (8), Timothy S. Blackwell (3, 4), Yoshinobu Ohira (2), Toshio Hirano (9, 10), Masaaki Murakami (1)
  1. Laboratory of Developmental Immunology, JST-CREST, Graduate School of Frontier Biosciences, Graduate School of Medicine, and WPI Immunology Frontier Research Center, Osaka University, Osaka 565-0871, Japan
  2. Department of Health and Sports Sciences, Graduate School of Medicine, and Graduate School of Frontier Biosciences, Osaka University, Osaka 560-0043, Japan
  3. Department of Cancer Biology, Vanderbilt University, TN 37232, USA
  4. Department of Medicine, Vanderbilt University, TN 37232, USA
  5. Radioisotope Research Institute, Department of Dental Medicine, Tsurumi University, Yokohama 230-8501, Japan
  6. Center for Experimental Medicine and Systems Biology, Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan
  7. Merck KGaA, Portfolio Development Merck Serono, 64293 Darmstadt, Germany
  8. National Center for Biotechnology (CNB-CSIC), Darwin 3, 28049 Madrid, Spain
  9. Osaka University, Osaka 565-0871, Japan
  10. Laboratory of Cytokine Signaling, RIKEN Research Center for Allergy and Immunology, Yokohama 230-0045, Japan

Contact:
Masaaki Murakami
murakami@molonc.med.osaka-u.ac.jp
Laboratory of Developmental Immunology, JST-CREST,
Graduate School of Frontier Biosciences, Graduate School of Medicine, and Immunology Frontier Research Center, Osaka University

Cell 148, 447–457 (2012)
22304915
2012-01 Two rotating cilia in the node cavity are sufficient to break left-right symmetry in the mouse embryo

Shinohara K*, Kawasumi A*, Takamatsu A, Yoshiba S, Botilde Y, Motoyama N, Reith W, Durand B, Shiratori H, Hamada H
* ; equal contribution

Nat Commun 3, 622 (2012)
22233632
2011-10 Energy transduction mechanism used in bacterial flagellar type III protein export

Tohru Minamino, Yusuke V. Morimoto, Noritaka Hara and Keiichi Namba

Nat Commun 2, 475 (2011)
21934659 Protonic NanoMachine Group 〈Prof. Namba〉
2011-09 Aneuploidy Drives Genomic Instability in Yeast

Jason M. Sheltzer (1), Heidi M. Blank (1), Sarah J. Pfau (1), Yoshie Tange (2), Benson M. George (1), Timothy J. Humpton (1), Ilana L. Brito (3), Yasushi Hiraoka (2, 4), Osami Niwa (5) and Angelika Amon (1)
  1. David H. Koch Institute for Integrative Cancer Research and Howard Hughes Medical Institute (HHMI)
  2. Graduate School of Frontier Biosciences, Osaka University
  3. Department of Ecology, Evolution and Environmental Biology, Columbia University
  4. Kobe Advanced ICT Research Center, National Institute of Information and Communications Technology
  5. The Rockefeller University


Science 333, 1026-1030 (2011)
21852501 Nuclear Dynamics Group 〈Prof. Hiraoka〉
2011-08 Reference frames for spatial frequency in face representation differ in the temporal visual cortex and amygdala

Inagaki M, Fujita I

J Neurosci 31, 10371-79 (2011)
21753014 Cognitive Neuroscience Group 〈Prof. Fujita〉
2011-06 Origin and role of distal visceral endoderm, a group of cells that determines anterior-posterior polarity of the mouse embryo

Takaoka K, Yamamoto M, Hamada H

Nat cell biol 13, 743-52 (2011)
21623358
2011-05 Tara up-regulates E-cadherin transcription by binding to the Trio RhoGEF and inhibiting Rac-signaling

Yano T (1), Yamazaki Y (1), Adachi M (2), Okawa K (3), Fort P (4), Uji M (1), Tsukita S (1, 2), Tsukita S (1)
  1. Laboratory of Biological Science, Graduate School of Frontier Biosciences and Graduate School of Medicine, Osaka University, Yamadaoka 2-2, Suita, Osaka 565-0871, Japan
  2. Department of Cell Biology, Faculty of Medicine, Kyoto University, Yoshida-Konoe, Sakyo-ku, Kyoto 606-8501, Japan
  3. Drug Discovery Research Laboratories, Kyowa Hakko Kirin Co., Ltd., Nagaizumi-machi, Shizuoka, 411-8731, Japan
  4. CRBM, UMSF, Université Montpellier 2 and 1, CNRS UMR 5237, Montpellier 34293, France


J Cell Biol 193, 319-32 (2011)
21482718 Biological Science Group 〈Prof. Tsukita〉